Pancreatic Organoids for Regenerative Medicine and Cancer Research

In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable model...

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Detalhes bibliográficos
Autores: Casamitjana, Joan, Espinet, Elisa, Rovira, Meritxell
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/194365
Acesso em linha:https://hdl.handle.net/2445/194365
Access Level:acceso abierto
Palavra-chave:Pàncrees
Diabetis
Medicina regenerativa
Medicina personalitzada
Pancreas
Diabetes
Regenerative medicine
Personalized medicine
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spelling Pancreatic Organoids for Regenerative Medicine and Cancer ResearchCasamitjana, JoanEspinet, ElisaRovira, MeritxellPàncreesDiabetisMedicina regenerativaMedicina personalitzadaPancreasDiabetesRegenerative medicinePersonalized medicineIn recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening.Frontiers Media2022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/194365Articles publicats en revistes (Ciències Fisiològiques)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3389/fcell.2022.886153Frontiers In Cell And Developmental Biology, 2022, vol. 10https://doi.org/10.3389/fcell.2022.886153cc-by (c) Casamitjana, Joan et al., 2022https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1943652026-05-27T06:46:51Z
dc.title.none.fl_str_mv Pancreatic Organoids for Regenerative Medicine and Cancer Research
title Pancreatic Organoids for Regenerative Medicine and Cancer Research
spellingShingle Pancreatic Organoids for Regenerative Medicine and Cancer Research
Casamitjana, Joan
Pàncrees
Diabetis
Medicina regenerativa
Medicina personalitzada
Pancreas
Diabetes
Regenerative medicine
Personalized medicine
title_short Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_full Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_fullStr Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_full_unstemmed Pancreatic Organoids for Regenerative Medicine and Cancer Research
title_sort Pancreatic Organoids for Regenerative Medicine and Cancer Research
dc.creator.none.fl_str_mv Casamitjana, Joan
Espinet, Elisa
Rovira, Meritxell
author Casamitjana, Joan
author_facet Casamitjana, Joan
Espinet, Elisa
Rovira, Meritxell
author_role author
author2 Espinet, Elisa
Rovira, Meritxell
author2_role author
author
dc.subject.none.fl_str_mv Pàncrees
Diabetis
Medicina regenerativa
Medicina personalitzada
Pancreas
Diabetes
Regenerative medicine
Personalized medicine
topic Pàncrees
Diabetis
Medicina regenerativa
Medicina personalitzada
Pancreas
Diabetes
Regenerative medicine
Personalized medicine
description In recent years, the development of ex vivo organoid cultures has gained substantial attention as a model to study regenerative medicine and diseases in several tissues. Diabetes and pancreatic ductal adenocarcinoma (PDAC) are the two major devastating diseases affecting the pancreas. Suitable models for regenerative medicine in diabetes and to accurately study PDAC biology and treatment response are essential in the pancreatic field. Pancreatic organoids can be generated from healthy pancreas or pancreatic tumors and constitute an important translational bridge between in vitro and in vivo models. Here, we review the rapidly emerging field of pancreatic organoids and summarize the current applications of the technology to tissue regeneration, disease modelling, and drug screening.
publishDate 2022
dc.date.none.fl_str_mv 2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/194365
url https://hdl.handle.net/2445/194365
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3389/fcell.2022.886153
Frontiers In Cell And Developmental Biology, 2022, vol. 10
https://doi.org/10.3389/fcell.2022.886153
dc.rights.none.fl_str_mv cc-by (c) Casamitjana, Joan et al., 2022
https://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Casamitjana, Joan et al., 2022
https://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Frontiers Media
publisher.none.fl_str_mv Frontiers Media
dc.source.none.fl_str_mv Articles publicats en revistes (Ciències Fisiològiques)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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