Safety of Obtaining an Extra Biobank Kidney Biopsy Core
Biobank; Chronic kidney disease; Kidney biopsy
| Autores: | , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2022 |
| País: | España |
| Institución: | Departament de Salut de la Generalitat de Catalunya (DS) |
| Repositorio: | Scientia. Dipòsit d'Informació Digital del Departament de Salut |
| OAI Identifier: | oai:scientiasalut.gencat.cat:11351/7907 |
| Acceso en línea: | https://hdl.handle.net/11351/7907 |
| Access Level: | acceso abierto |
| Palabra clave: | Ronyons - Malalties - Diagnòstic Ronyons - Malalties - Biòpsia DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases Other subheadings::Other subheadings::/diagnosis ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales Otros calificadores::Otros calificadores::/diagnóstico |
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Safety of Obtaining an Extra Biobank Kidney Biopsy CoreBermejo Garcia, SheilaGarcía Carro, ClaraMast, RichardVergara Arana, AnderAgraz Pamplona, IreneLeón Román, JuanBolufer Cardona, MonicaGabaldon Dominguez, AlejandraSerón Micas, DanielBestard Matamoros, OriolSoler Romeo, Maria JoseRonyons - Malalties - DiagnòsticRonyons - Malalties - BiòpsiaDISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney DiseasesOther subheadings::Other subheadings::/diagnosisENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renalesOtros calificadores::Otros calificadores::/diagnósticoBiobank; Chronic kidney disease; Kidney biopsyBiobanco; Enfermedad renal cronica; Biopsia renalBiobanc; Malaltia renal crònica; Biòpsia de ronyóBackground and objectives: Kidney biopsy (KB) is the “gold standard” for the diagnosis of nephropathies and it is a diagnostic tool that presents a low rate of complications. Nowadays, biobank collections of renal tissue of patients with proven renal pathology are essential for research in nephrology. To provide enough tissue for the biobank collection, it is usually needed to obtain an extra kidney core at the time of kidney biopsy. The objective of our study is to evaluate the complications after KB and to analyze whether obtaining an extra core increases the risk of complications. Material and methods: Prospective observational study of KBs performed at Vall d’Hebron Hospital between 2019 and 2020. All patients who accepted to participate to our research biobank of native kidney biopsies were included to the study. Clinical and laboratory data were reviewed and we studied risk factors associated with complications. Results: A total of 221 patients were included, mean age 56.6 (±16.8) years, 130 (58.8%) were men, creatinine was 2.24 (±1.94) mg/dL, proteinuria 1.56 (0.506–3.590) g/24 h, hemoglobin 12.03 (±2.3) g/dL, INR 0.99 (±0.1), and prothrombin time (PT) 11.86 (±1.2) s. A total of 38 patients (17.2%) presented complications associated with the procedure: 13.1% were minor complications, 11.3% (n = 25) required blood transfusion, 1.4% (n = 3) had severe hematomas, 2.3% (n = 5) required embolization, and 0.5% (n = 1) presented arterio-venous fistula. An increased risk for complication was independently associated with obtaining a single kidney core (vs. 2 and 3 cores) (p = 0.021). Conclusions: KB is an invasive and safe procedure with a low percentage of complications. Obtaining an extra kidney core for research does not increase the risk of complications during the intervention, which remains low in concordance with previously published reports.The authors are current recipients of research grant from Red de Investigación Renal (REDINREN, RD16/0009/0030). (RICORS, RD21/0005/0016).MDPIInstitut Català de la Salut[Bermejo S, Vergara A, Agraz I, León JC, Bolufer M, Serón D, Bestard O, Soler MJ] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [García-Carro C] Nephrology Department, Hospital Clínico San Carlos, 28940 Madrid, Spain. [Mast R] Servei de Radiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Gabaldon MA] Servei de Patologia, Vall d’Hebron Hospital Universitari, Barcelona, SpainVall d'Hebron Barcelona Hospital Campus202220222022info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/11351/7907Scientiareponame:Scientia. Dipòsit d'Informació Digital del Departament de Salutinstname:Departament de Salut de la Generalitat de Catalunya (DS)InglésJournal of Clinical Medicine;11(5)https://doi.org/10.3390/jcm11051459info:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0009%2F0030info:eu-repo/grantAgreement/ES/PE2017-2020/RD21%2F0005%2F0016Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:scientiasalut.gencat.cat:11351/79072026-06-12T09:38:37Z |
| dc.title.none.fl_str_mv |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| title |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| spellingShingle |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core Bermejo Garcia, Sheila Ronyons - Malalties - Diagnòstic Ronyons - Malalties - Biòpsia DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases Other subheadings::Other subheadings::/diagnosis ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales Otros calificadores::Otros calificadores::/diagnóstico |
| title_short |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| title_full |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| title_fullStr |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| title_full_unstemmed |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| title_sort |
Safety of Obtaining an Extra Biobank Kidney Biopsy Core |
| dc.creator.none.fl_str_mv |
Bermejo Garcia, Sheila García Carro, Clara Mast, Richard Vergara Arana, Ander Agraz Pamplona, Irene León Román, Juan Bolufer Cardona, Monica Gabaldon Dominguez, Alejandra Serón Micas, Daniel Bestard Matamoros, Oriol Soler Romeo, Maria Jose |
| author |
Bermejo Garcia, Sheila |
| author_facet |
Bermejo Garcia, Sheila García Carro, Clara Mast, Richard Vergara Arana, Ander Agraz Pamplona, Irene León Román, Juan Bolufer Cardona, Monica Gabaldon Dominguez, Alejandra Serón Micas, Daniel Bestard Matamoros, Oriol Soler Romeo, Maria Jose |
| author_role |
author |
| author2 |
García Carro, Clara Mast, Richard Vergara Arana, Ander Agraz Pamplona, Irene León Román, Juan Bolufer Cardona, Monica Gabaldon Dominguez, Alejandra Serón Micas, Daniel Bestard Matamoros, Oriol Soler Romeo, Maria Jose |
| author2_role |
author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Institut Català de la Salut [Bermejo S, Vergara A, Agraz I, León JC, Bolufer M, Serón D, Bestard O, Soler MJ] Servei de Nefrologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [García-Carro C] Nephrology Department, Hospital Clínico San Carlos, 28940 Madrid, Spain. [Mast R] Servei de Radiologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Gabaldon MA] Servei de Patologia, Vall d’Hebron Hospital Universitari, Barcelona, Spain Vall d'Hebron Barcelona Hospital Campus |
| dc.subject.none.fl_str_mv |
Ronyons - Malalties - Diagnòstic Ronyons - Malalties - Biòpsia DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases Other subheadings::Other subheadings::/diagnosis ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales Otros calificadores::Otros calificadores::/diagnóstico |
| topic |
Ronyons - Malalties - Diagnòstic Ronyons - Malalties - Biòpsia DISEASES::Male Urogenital Diseases::Urologic Diseases::Kidney Diseases Other subheadings::Other subheadings::/diagnosis ENFERMEDADES::enfermedades urogenitales masculinas::enfermedades urológicas::enfermedades renales Otros calificadores::Otros calificadores::/diagnóstico |
| description |
Biobank; Chronic kidney disease; Kidney biopsy |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022 2022 2022 |
| dc.type.none.fl_str_mv |
info:eu-repo/semantics/article info:eu-repo/semantics/publishedVersion |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/11351/7907 |
| url |
https://hdl.handle.net/11351/7907 |
| dc.language.none.fl_str_mv |
Inglés |
| language_invalid_str_mv |
Inglés |
| dc.relation.none.fl_str_mv |
Journal of Clinical Medicine;11(5) https://doi.org/10.3390/jcm11051459 info:eu-repo/grantAgreement/ES/PE2013-2016/RD16%2F0009%2F0030 info:eu-repo/grantAgreement/ES/PE2017-2020/RD21%2F0005%2F0016 |
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Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
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Attribution 4.0 International http://creativecommons.org/licenses/by/4.0/ |
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openAccess |
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application/pdf |
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MDPI |
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MDPI |
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Scientia reponame:Scientia. Dipòsit d'Informació Digital del Departament de Salut instname:Departament de Salut de la Generalitat de Catalunya (DS) |
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Departament de Salut de la Generalitat de Catalunya (DS) |
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Scientia. Dipòsit d'Informació Digital del Departament de Salut |
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Scientia. Dipòsit d'Informació Digital del Departament de Salut |
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