Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations
Background: Different types of therapies were proven effective for the medical management of motor and non-motor symptoms in Parkinson's disease (PD). We aimed to gain consensus on the dopamine agonist (DA) therapy use in different clinical scenarios of Parkinson's disease (PD) patients. M...
| Autores: | , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2023 |
| País: | España |
| Institución: | Universidad de Cantabria (UC) |
| Repositorio: | UCrea Repositorio Abierto de la Universidad de Cantabria |
| Idioma: | español inglés |
| OAI Identifier: | oai:repositorio.unican.es:10902/36011 |
| Acceso en línea: | https://hdl.handle.net/10902/36011 |
| Access Level: | acceso abierto |
| Palabra clave: | Dopamine agonist Parkinson’s disease Expert consensus |
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oai:repositorio.unican.es:10902/36011 |
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España |
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Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations Tratamiento con agonistas dopaminérgicos en la enfermedad de Parkinson: consenso de expertos españoles sobre su uso en diferentes situaciones clínicas |
| title |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| spellingShingle |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations Santos García, Diego Dopamine agonist Parkinson’s disease Expert consensus |
| title_short |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| title_full |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| title_fullStr |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| title_full_unstemmed |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| title_sort |
Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situations |
| dc.creator.none.fl_str_mv |
Santos García, Diego Pagonabarraga Mora, J. Escamilla Sevilla, F. García Ruiz, P.J. Infante Ceberio, Jon|||0000-0003-4025-4606 Kulisevsky Bojarski, J. Linazasoro Cristóbal, G. Luquín Piudo, M.R. Martínez Castrillo, J.C. Jesús Maestre, S. Vela Desojo, L. Campos Lucas, F.J. Caballero Martínez, F. |
| author |
Santos García, Diego |
| author_facet |
Santos García, Diego Pagonabarraga Mora, J. Escamilla Sevilla, F. García Ruiz, P.J. Infante Ceberio, Jon|||0000-0003-4025-4606 Kulisevsky Bojarski, J. Linazasoro Cristóbal, G. Luquín Piudo, M.R. Martínez Castrillo, J.C. Jesús Maestre, S. Vela Desojo, L. Campos Lucas, F.J. Caballero Martínez, F. |
| author_role |
author |
| author2 |
Pagonabarraga Mora, J. Escamilla Sevilla, F. García Ruiz, P.J. Infante Ceberio, Jon|||0000-0003-4025-4606 Kulisevsky Bojarski, J. Linazasoro Cristóbal, G. Luquín Piudo, M.R. Martínez Castrillo, J.C. Jesús Maestre, S. Vela Desojo, L. Campos Lucas, F.J. Caballero Martínez, F. |
| author2_role |
author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Universidad de Cantabria |
| dc.subject.none.fl_str_mv |
Dopamine agonist Parkinson’s disease Expert consensus |
| topic |
Dopamine agonist Parkinson’s disease Expert consensus |
| description |
Background: Different types of therapies were proven effective for the medical management of motor and non-motor symptoms in Parkinson's disease (PD). We aimed to gain consensus on the dopamine agonist (DA) therapy use in different clinical scenarios of Parkinson's disease (PD) patients. Methods: This consensus study was based on the nominal group technique. Initially, a consensus group comprising 12 expert neurologists in the PD field identified the topics to be addressed and elaborated different evidence-based preliminary statements. Next, a panel of 48 Spanish neurologists expressed their opinion on an internet-based systematic voting program. Finally, initial ideas were reviewed and rewritten according to panel contribution and were ranked by the consensus group using a Likert-type scale. The analysis of data was carried out by using a combination of both qualitative and quantitative methods. The consensus was achieved if the statement reached ≥ 3.5 points in the voting process. Results: The consensus group produced 76 real-world recommendations. The topics addressed included 12 statements related to DA therapy in early PD, 20 statements concerning DA treatment strategy in patients with motor complications, 11 statements associated with DA drugs and their side effects, and 33 statements regarding DA therapy in specific clinical scenarios. The consensus group did not reach a consensus on 15 statements. Conclusion: The findings from this consensus method represent an exploratory step to help clinicians and patients in the appropriate use of DA in different stages and clinical situations of PD. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023 2023-01-01 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 NA http://purl.org/coar/version/c_be7fb7dd8ff6fe43 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10902/36011 |
| url |
https://hdl.handle.net/10902/36011 |
| dc.language.none.fl_str_mv |
Español spa Inglés eng |
| language_invalid_str_mv |
Español Inglés |
| language |
spa eng |
| dc.rights.none.fl_str_mv |
open access http://purl.org/coar/access_right/c_abf2 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
| dc.rights.openaire.fl_str_mv |
info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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openAccess |
| dc.publisher.none.fl_str_mv |
Elsevier Doyma |
| publisher.none.fl_str_mv |
Elsevier Doyma |
| dc.source.none.fl_str_mv |
Neurología, 2023, 5, S2173-5808(23)00037-8 reponame:UCrea Repositorio Abierto de la Universidad de Cantabria instname:Universidad de Cantabria (UC) |
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Universidad de Cantabria (UC) |
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UCrea Repositorio Abierto de la Universidad de Cantabria |
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UCrea Repositorio Abierto de la Universidad de Cantabria |
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1869402827569233920 |
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Dopamine agonist therapy in Parkinson's disease: Spanish expert consensus on its use in different clinical situationsTratamiento con agonistas dopaminérgicos en la enfermedad de Parkinson: consenso de expertos españoles sobre su uso en diferentes situaciones clínicasSantos García, DiegoPagonabarraga Mora, J.Escamilla Sevilla, F.García Ruiz, P.J.Infante Ceberio, Jon|||0000-0003-4025-4606Kulisevsky Bojarski, J.Linazasoro Cristóbal, G.Luquín Piudo, M.R.Martínez Castrillo, J.C.Jesús Maestre, S.Vela Desojo, L.Campos Lucas, F.J.Caballero Martínez, F.Dopamine agonistParkinson’s diseaseExpert consensusBackground: Different types of therapies were proven effective for the medical management of motor and non-motor symptoms in Parkinson's disease (PD). We aimed to gain consensus on the dopamine agonist (DA) therapy use in different clinical scenarios of Parkinson's disease (PD) patients. Methods: This consensus study was based on the nominal group technique. Initially, a consensus group comprising 12 expert neurologists in the PD field identified the topics to be addressed and elaborated different evidence-based preliminary statements. Next, a panel of 48 Spanish neurologists expressed their opinion on an internet-based systematic voting program. Finally, initial ideas were reviewed and rewritten according to panel contribution and were ranked by the consensus group using a Likert-type scale. The analysis of data was carried out by using a combination of both qualitative and quantitative methods. The consensus was achieved if the statement reached ≥ 3.5 points in the voting process. Results: The consensus group produced 76 real-world recommendations. The topics addressed included 12 statements related to DA therapy in early PD, 20 statements concerning DA treatment strategy in patients with motor complications, 11 statements associated with DA drugs and their side effects, and 33 statements regarding DA therapy in specific clinical scenarios. The consensus group did not reach a consensus on 15 statements. Conclusion: The findings from this consensus method represent an exploratory step to help clinicians and patients in the appropriate use of DA in different stages and clinical situations of PD.Antecedentes: Se demostró la efectividad de diferentes tipos de terapias para el tratamiento médico de los síntomas motores y no motores en la enfermedad de Parkinson (EP). Nos propusimos lograr un consenso sobre el uso de la terapia con agonistas dopaminérgicos (DA) en diferentes escenarios clínicos de pacientes con enfermedad de Parkinson (EP). Métodos: Este estudio de consenso se basó en la técnica de grupo nominal. Inicialmente, un Grupo de Consenso formado por 12 neurólogos expertos en el campo de la EP identificó los temas a tratar y elaboró diferentes declaraciones preliminares basadas en la evidencia. A continuación, un panel de 48 neurólogos españoles ? expresó su opinión en un programa de votación sistemática a través de Internet. Finalmente, las ideas iniciales fueron revisadas y reescritas de acuerdo con la contribución del panel y fueron clasificadas por el grupo de Consenso utilizando una escala tipo Likert. El análisis de los datos se llevó a cabo mediante una combinación de métodos cualitativos y cuantitativos. El consenso se alcanzaba si la afirmación alcanzaba ≥3,5 puntos en el proceso de votación. Resultados: El Grupo de Consenso elaboró 76 recomendaciones para el mundo real. Los temas abordados incluyeron 12 afirmaciones relacionadas con la terapia con DA en la EP temprana, 20 afirmaciones relativas a la estrategia de tratamiento con DA en pacientes con complicaciones motoras, 11 afirmaciones asociadas con los fármacos DA y sus efectos secundarios, y 33 afirmaciones relativas a la terapia con DA en escenarios clínicos específicos. El Grupo de Consenso no llegó a un consenso en 15 afirmaciones. Conclusiones: Los resultados de este método de consenso representan un paso exploratorio para ayudar a clínicos y pacientes en el uso apropiado de la DA en diferentes estadios y situaciones clínicas de la EP.Funding: This study was funded by the Chair of Epilepsy and Movement Disorders UFV-UCB. Acknowledgement: We thank the neurologists who participated in phase 1 for their disinterested collaboration. We thank the Epilepsy and Movement Disorders UFV-UCB Chair for supporting this initiative. We thank Irene Santamaría of the Francisco de Vitoria University for the technical coordination work of this study.Elsevier DoymaUniversidad de Cantabria20232023-01-01journal articlehttp://purl.org/coar/resource_type/c_6501NAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/articlehttps://hdl.handle.net/10902/36011Neurología, 2023, 5, S2173-5808(23)00037-8reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)EspañolspaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/360112026-06-02T12:39:31Z |
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15,812429 |