Conditional Poisson models: a flexible alternative to conditional logistic case cross-over analysis

[Background] The time stratified case cross-over approach is a popular alternative to conventional time series regression for analysing associations between time series of environmental exposures (air pollution, weather) and counts of health outcomes. These are almost always analyzed using condition...

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Detalles Bibliográficos
Autores: Armstrong, Ben, Gasparrini, Antonio, Tobías, Aurelio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/125815
Acceso en línea:http://hdl.handle.net/10261/125815
Access Level:acceso abierto
Palabra clave:Statistics
Conditional distributions
Poisson regression
Time series regression
Environment
Descripción
Sumario:[Background] The time stratified case cross-over approach is a popular alternative to conventional time series regression for analysing associations between time series of environmental exposures (air pollution, weather) and counts of health outcomes. These are almost always analyzed using conditional logistic regression on data expanded to case–control (case crossover) format, but this has some limitations. In particular adjusting for overdispersion and auto-correlation in the counts is not possible. It has been established that a Poisson model for counts with stratum indicators gives identical estimates to those from conditional logistic regression and does not have these limitations, but it is little used, probably because of the overheads in estimating many stratum parameters.