Trends in the epidemiology of catheter-related bloodstream infections

Background: Catheter-related bloodstream infections (CRBSI) are frequent healthcare-associated infections and an important cause of death. Aim: To analyse changes in CRBSI epidemiology observed by the Infection Control Catalan Programme (VINCat). Methods: A cohort study including all hospital-acquir...

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Authors: Badia Cebada, Laia|||0000-0002-9321-8492, Peñafiel, Judit, Saliba, Patrick, Andrés Nieto, Marta|||0000-0001-5267-0039, Càmara, Jordi|||0000-0002-0817-0931, Domènech, Dolors, Jiménez-Martínez, Emili, Marrón, Anna, Moreno, Encarna, Pomar, Virginia|||0000-0002-8473-5834, Vaqué, Montserrat, Limón, Enric|||0000-0002-5396-1521, Masats, Úrsula, Pujol, Miquel|||0000-0002-6475-6208, Gasch Blasi, Oriol|||0000-0001-8518-458X, Jover, Alfredo, Castellana, Dolors, Olona, Montserrat|||0000-0001-5303-9361, García Pino, Antonia, Rebull Fatsini, Josep|||0000-0002-1460-8290, Domènech, Mª France, Hornero, Ana, Ardanuy, Carmen|||0000-0003-0225-607X, Berbel Palau, Dàmaris, López-Contreras, Joaquín|||0000-0002-3166-4016, Fernández, Engracia, Salgado, Xavier, Lérida, Ana, Martin, Lydia, Sopena, Nieves|||0000-0001-6382-9500, Casas, Irma|||0000-0002-5902-5777, Pérez, Rafael, Maraver, Encarna, Palau, Eva, Serrats, Pepi, Martínez, José Antonio, Santana, Gemina, Martínez, Ana, Ferrer, Lourdes, Moreno, Mª José, Calbo Sebastián, Esther|||0000-0001-7750-5347, Porta, Carolina, Smithson, Alex, de la Roca Toda, Maria, Aliu, Teresa, Camps, Susana, Ortega, Montserrat, Diaz-Brito, Vicens, Agusti, Carme, Perea Garcia, Miquel, Grau Palafox, Laura, Carrera, Raquel, Besolí, Anna, Horcajada, Juan Pablo|||0000-0001-9873-5459, Gonzalez, Cristina, Cuquet, Jordi, Maldonado López, Demelsa Maria, Benítez Díaz, Rosa María|||0000-0001-6972-6094, Duch, Mireia, Blancas, David, Moreno, Esther, Villalba, Naiara, Martínez, Sara, García Flores, Àngels, Ferrer, Roser, Bisbe, Josep, Blascó, Montse, Castro Salom, Antoni, López, Ana Felisa, Espinach Alvarós, Joan, Perez, Àngels, Castander, David, Calaf, Elisabet, Clarós, Mercè, Bosch Ros, Núria, Montardit, Irene, Porta, Roser, De la Cruz Sol, Pilar, Coll Colell, Mª Rosa, García Penche Sanches, Rosa, Tricas, Josep Maria, Redon, Eva, Brugués, Montse, Linares González, Laura|||0000-0001-5738-631X, Cusco, Maria, Barrufet, Mª Pilar, Vidal, Elena, Barbadillo, Sandra, Marimón, Mariló, Meije, Yolanda, Laplace Enguinados, M.Rosa, Vila, Blanca, Coloma, Ana Guadalupe, López, Lucrecia, Campins Martí, Magda|||0000-0002-8841-6195, Almirante Gragera, Benito|||0000-0002-1189-2361, Ferrer, Carme, Juan Serra, Natalia, Farguell Carrera, Josep, Milian Sanz, Marta, Moise, Alexandra, Jiménez Zarate, Ana Mª, Eito Navasal, M. Carmen, Garcia Ramirez, María Gracia, Armario Fernández, Mar
Format: article
Publication Date:2022
Country:España
Institution:Universitat Autònoma de Barcelona
Repository:Dipòsit Digital de Documents de la UAB
Language:English
OAI Identifier:oai:ddd.uab.cat:275187
Online Access:https://ddd.uab.cat/record/275187
https://dx.doi.org/urn:doi:10.2807/1560-7917.ES.2022.27.19.2100610
Access Level:Open access
Keyword:Bacteremia
Catheter-Related Infections
Catheterization, Central Venous
Catheters
Cohort Studies
Female
Humans
Incidence
Male
Middle Aged
Polyvinyl Chloride
Prospective Studies
Sepsis
Spain
Description
Summary:Background: Catheter-related bloodstream infections (CRBSI) are frequent healthcare-associated infections and an important cause of death. Aim: To analyse changes in CRBSI epidemiology observed by the Infection Control Catalan Programme (VINCat). Methods: A cohort study including all hospital-acquired CRBSI episodes diagnosed at 55 hospitals (2007-2019) in Catalonia, Spain, was prospectively conducted. CRBSI incidence rates were adjusted per 1,000patientdays. To assess the CRBSI rate trend per year, negative binomial models were used, with the number of events as the dependent variable, and the year as the main independent variable. From each model, the annual rate of CRBSI diagnosed per 1,000patientdays and the incidence rate ratio (IRR) with its 95% confidence intervals (CI) were reported. Results: During the study, 9,290 CRBSI episodes were diagnosed (mean annual incidence rate:0.20episodes/1,000patientdays). Patients' median age was 64.1years; 36.6% (3,403/9,290) were female. In total, 73.7% (n=6,845) of CRBSI occurred in non-intensive care unit (ICU) wards, 62.7% (n=5,822) were related to central venous catheter (CVC), 24.1% (n=2,236) to peripheral venous catheters (PVC) and 13.3% (n=1,232) to peripherally-inserted central venous catheters (PICVC). Incidence rate fell over the study period (IRR:0.94;95%CI:0.93-0.96), especially in the ICU (IRR:0.88;95%CI:0.87-0.89). As a whole, while episodes of CVC CRBSI fell significantly (IRR:0.88;95%CI:0.87-0.91), peripherally-inserted catheter CRBSI (PVC and PICVC) rose, especially in medical wards (IRR PICVC:1.08;95%CI:1.05-1.11; IRR PVC: 1.03; 95% 1.00-1.05). Conclusions: Over the study, CRBSIs associated with CVC and diagnosed in ICUs decreased while episodes in conventional wards involving peripherally-inserted catheters increased. Hospitals should implement preventive measures in conventional wards.

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