Molecular characterisation of triple negative essential thrombocythaemia patients by platelet analysis and targeted sequencing.

Essential thrombocythaemia (ET) is a myeloproliferative neoplasm(MPN) characterised by megakaryocyte hyperplasia and thrombo-cytosis. From the genetic perspective, ET patients harbourmutations inJAK2(50–60%),CALR(15–30%) andMPL(1–5%) genes.

Detalhes bibliográficos
Autores: Angona Figueras, Anna, Fernández Rodríguez, M. Concepción, Álvarez Larrán, Alberto, Camacho Díaz, Laura, Longarón Rozalen, Raquel, Torres, Erica, Pairet García, Silvia, Besses Raebel, Carles, Bellosillo Paricio, Beatriz
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2016
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositório:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10230/27900
Acesso em linha:http://hdl.handle.net/10230/27900
http://dx.doi.org/10.1038/bcj.2016.75
Access Level:Acceso aberto
Palavra-chave:Trombocitèmia
Plaquetes sanguínies -- Trastorns
Descrição
Resumo:Essential thrombocythaemia (ET) is a myeloproliferative neoplasm(MPN) characterised by megakaryocyte hyperplasia and thrombo-cytosis. From the genetic perspective, ET patients harbourmutations inJAK2(50–60%),CALR(15–30%) andMPL(1–5%) genes.

Registros relacionados