Will we ever eradicate animal tuberculosis?

Two characteristics of the Mycobacterium tuberculosis complex (MTC) are particularly relevant for tuberculosis (TB) epidemiology and control, namely the ability of this group of pathogens to survive in the environment and thereby facilitate indirect transmission via water or feed, and the capacity t...

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Authors: Perelló , A, Domínguez , Lucas, Gortázar Schmidt, Ramón Christian, Fuente García, José de Jesús de la
Format: article
Publication Date:2023
Country:España
Institution:Universidad de Castilla-La Mancha
Repository:RUIdeRA. Repositorio Institucional de la UCLM
OAI Identifier:oai:ruidera.uclm.es:10578/33019
Online Access:https://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-023-00254-9
https://hdl.handle.net/10578/33019
Access Level:Open access
Keyword:Acceptability of control options
Farm biosafety
Integrated disease control
Maintenance host community
Test and cull
Vaccination
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spelling Will we ever eradicate animal tuberculosis?Perelló , ADomínguez , LucasGortázar Schmidt, Ramón ChristianFuente García, José de Jesús de laAcceptability of control optionsFarm biosafetyIntegrated disease controlMaintenance host communityTest and cullVaccinationTwo characteristics of the Mycobacterium tuberculosis complex (MTC) are particularly relevant for tuberculosis (TB) epidemiology and control, namely the ability of this group of pathogens to survive in the environment and thereby facilitate indirect transmission via water or feed, and the capacity to infect multiple host species including human beings, cattle, wildlife, and domestic animals other than cattle. As a consequence, rather than keeping the focus on certain animal species regarded as maintenance hosts, we postulate that it is time to think of complex and dynamic multi-host MTC maintenance communities where several wild and domestic species and the environment contribute to pathogen maintenance. Regarding the global situation of animal TB, many industrialized countries have reached the Officially Tuberculosis Free status. However, infection of cattle with M. bovis still occurs in most countries around the world. In low- and middle-income countries, human and animal TB infection is endemic and bovine TB control programs are often not implemented because standard TB control through testing and culling, movement control and slaughterhouse inspection is too expensive or ethically unacceptable. In facing increasingly complex epidemiological scenarios, modern integrated disease control should rely on three main pillars: (1) a close involvement of farmers including collaborative decision making, (2) expanding the surveillance and control targets to all three host categories, the environment, and their interactions, and (3) setting up new control schemes or upgrading established ones switching from single tool test and cull approaches to integrated ones including farm biosafety and vaccination.Jude Publications202420242023info:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-023-00254-9https://hdl.handle.net/10578/33019reponame:RUIdeRA. Repositorio Institucional de la UCLMinstname:Universidad de Castilla-La ManchaInglésinfo:eu-repo/semantics/openAccessoai:ruidera.uclm.es:10578/330192026-05-27T07:36:41Z
dc.title.none.fl_str_mv Will we ever eradicate animal tuberculosis?
title Will we ever eradicate animal tuberculosis?
spellingShingle Will we ever eradicate animal tuberculosis?
Perelló , A
Acceptability of control options
Farm biosafety
Integrated disease control
Maintenance host community
Test and cull
Vaccination
title_short Will we ever eradicate animal tuberculosis?
title_full Will we ever eradicate animal tuberculosis?
title_fullStr Will we ever eradicate animal tuberculosis?
title_full_unstemmed Will we ever eradicate animal tuberculosis?
title_sort Will we ever eradicate animal tuberculosis?
dc.creator.none.fl_str_mv Perelló , A
Domínguez , Lucas
Gortázar Schmidt, Ramón Christian
Fuente García, José de Jesús de la
author Perelló , A
author_facet Perelló , A
Domínguez , Lucas
Gortázar Schmidt, Ramón Christian
Fuente García, José de Jesús de la
author_role author
author2 Domínguez , Lucas
Gortázar Schmidt, Ramón Christian
Fuente García, José de Jesús de la
author2_role author
author
author
dc.subject.none.fl_str_mv Acceptability of control options
Farm biosafety
Integrated disease control
Maintenance host community
Test and cull
Vaccination
topic Acceptability of control options
Farm biosafety
Integrated disease control
Maintenance host community
Test and cull
Vaccination
description Two characteristics of the Mycobacterium tuberculosis complex (MTC) are particularly relevant for tuberculosis (TB) epidemiology and control, namely the ability of this group of pathogens to survive in the environment and thereby facilitate indirect transmission via water or feed, and the capacity to infect multiple host species including human beings, cattle, wildlife, and domestic animals other than cattle. As a consequence, rather than keeping the focus on certain animal species regarded as maintenance hosts, we postulate that it is time to think of complex and dynamic multi-host MTC maintenance communities where several wild and domestic species and the environment contribute to pathogen maintenance. Regarding the global situation of animal TB, many industrialized countries have reached the Officially Tuberculosis Free status. However, infection of cattle with M. bovis still occurs in most countries around the world. In low- and middle-income countries, human and animal TB infection is endemic and bovine TB control programs are often not implemented because standard TB control through testing and culling, movement control and slaughterhouse inspection is too expensive or ethically unacceptable. In facing increasingly complex epidemiological scenarios, modern integrated disease control should rely on three main pillars: (1) a close involvement of farmers including collaborative decision making, (2) expanding the surveillance and control targets to all three host categories, the environment, and their interactions, and (3) setting up new control schemes or upgrading established ones switching from single tool test and cull approaches to integrated ones including farm biosafety and vaccination.
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-023-00254-9
https://hdl.handle.net/10578/33019
url https://irishvetjournal.biomedcentral.com/articles/10.1186/s13620-023-00254-9
https://hdl.handle.net/10578/33019
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Jude Publications
publisher.none.fl_str_mv Jude Publications
dc.source.none.fl_str_mv reponame:RUIdeRA. Repositorio Institucional de la UCLM
instname:Universidad de Castilla-La Mancha
instname_str Universidad de Castilla-La Mancha
reponame_str RUIdeRA. Repositorio Institucional de la UCLM
collection RUIdeRA. Repositorio Institucional de la UCLM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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