A multiple health behaviour change intervention to prevent depression: A randomized controlled trial

Objective: To examine the effectiveness of a 12-month MHBC intervention in the prevention of onset depression in primary health care (PHC). Methods: Twenty-two PHC centres took part in the cluster-randomized controlled trial. Patients were randomized to receive either usual care or an MHBC intervent...

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Autores: Gómez-Gómez, Irene, Motrico, Emma, Moreno-Peral, Patricia, Casajuana-Closas, Marc, López-Jiménez, Tomàs, Zabaleta-Del-Olmo, Edurne, Clavería, Ana, Llobera Cànaves, Joan, Martí-Lluch, Ruth, Ramos, Rafael, Maderuelo-Fernández, José-Ángel, Vicens-Caldentey, Caterina, Domínguez-García, Marta, Bartolomé-Moreno, Cruz, Recio-Rodriguez, Jose I, Bellón, Juan Á
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Instituto de Salud Carlos III (ISCIII)
Repositorio:Repisalud
Idioma:inglés
OAI Identifier:oai:repisalud.isciii.es:20.500.12105/23573
Acceso en línea:https://hdl.handle.net/20.500.12105/23573
Access Level:acceso abierto
Palabra clave:Ejercicio Físico
Trastorno Depresivo Mayor
Humanos
Depresión
Conductas Relacionadas con la Salud
Health Behavior
Depressive Disorder, Major
Humans
Depression
Exercise
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spelling A multiple health behaviour change intervention to prevent depression: A randomized controlled trialGómez-Gómez, IreneMotrico, EmmaMoreno-Peral, PatriciaCasajuana-Closas, MarcLópez-Jiménez, TomàsZabaleta-Del-Olmo, EdurneClavería, AnaLlobera Cànaves, JoanMartí-Lluch, RuthRamos, RafaelMaderuelo-Fernández, José-ÁngelVicens-Caldentey, CaterinaDomínguez-García, MartaBartolomé-Moreno, CruzRecio-Rodriguez, Jose IBellón, Juan ÁEjercicio FísicoTrastorno Depresivo MayorHumanosDepresiónConductas Relacionadas con la SaludHealth BehaviorDepressive Disorder, MajorHumansDepressionExerciseObjective: To examine the effectiveness of a 12-month MHBC intervention in the prevention of onset depression in primary health care (PHC). Methods: Twenty-two PHC centres took part in the cluster-randomized controlled trial. Patients were randomized to receive either usual care or an MHBC intervention. The endpoints were onset of major depression and reduction of depressive symptoms in participants without baseline depression at a 12-month follow-up. Results: 2531 patients agreed and were eligible to participate. At baseline, around 43% were smokers, 82% were non-adherent to the Mediterranean diet and 55% did not perform enough physical activity. The intervention group exhibited a greater positive change in two or more behaviours (OR 1.75 [95%CI: 1.17 to 2.62]; p = 0.006); any behaviour (OR 1.58 [95%CI: 1.13 to 2.20]; p = 0.007); and adherence to the Mediterranean diet (OR 1.94 [95%CI: 1.29 to 2.94]; p = 0.002), while this increase was not statistically significant for smoking and physical activity. The intervention was not effective in preventing major depression (OR 1.17; [95% CI 0.53 to 2.59)]; p = 0.690) or reducing depressive symptoms (Mean difference: 0.30; [95% CI -0.77 to 1.36]; p = 0.726) during follow-up. Conclusions: As compared to usual care, the MHBC intervention provided a non-significant reduction in the incidence of major depression. Trial registration: ClinicalTrials.gov, NCT03136211.Elsevier20242024-10-0920232023-01-0120232023-01-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articlehttps://hdl.handle.net/20.500.12105/23573reponame:Repisaludinstname:Instituto de Salud Carlos III (ISCIII)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:repisalud.isciii.es:20.500.12105/235732026-06-12T12:43:37Z
dc.title.none.fl_str_mv A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
title A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
spellingShingle A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
Gómez-Gómez, Irene
Ejercicio Físico
Trastorno Depresivo Mayor
Humanos
Depresión
Conductas Relacionadas con la Salud
Health Behavior
Depressive Disorder, Major
Humans
Depression
Exercise
title_short A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
title_full A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
title_fullStr A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
title_full_unstemmed A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
title_sort A multiple health behaviour change intervention to prevent depression: A randomized controlled trial
dc.creator.none.fl_str_mv Gómez-Gómez, Irene
Motrico, Emma
Moreno-Peral, Patricia
Casajuana-Closas, Marc
López-Jiménez, Tomàs
Zabaleta-Del-Olmo, Edurne
Clavería, Ana
Llobera Cànaves, Joan
Martí-Lluch, Ruth
Ramos, Rafael
Maderuelo-Fernández, José-Ángel
Vicens-Caldentey, Caterina
Domínguez-García, Marta
Bartolomé-Moreno, Cruz
Recio-Rodriguez, Jose I
Bellón, Juan Á
author Gómez-Gómez, Irene
author_facet Gómez-Gómez, Irene
Motrico, Emma
Moreno-Peral, Patricia
Casajuana-Closas, Marc
López-Jiménez, Tomàs
Zabaleta-Del-Olmo, Edurne
Clavería, Ana
Llobera Cànaves, Joan
Martí-Lluch, Ruth
Ramos, Rafael
Maderuelo-Fernández, José-Ángel
Vicens-Caldentey, Caterina
Domínguez-García, Marta
Bartolomé-Moreno, Cruz
Recio-Rodriguez, Jose I
Bellón, Juan Á
author_role author
author2 Motrico, Emma
Moreno-Peral, Patricia
Casajuana-Closas, Marc
López-Jiménez, Tomàs
Zabaleta-Del-Olmo, Edurne
Clavería, Ana
Llobera Cànaves, Joan
Martí-Lluch, Ruth
Ramos, Rafael
Maderuelo-Fernández, José-Ángel
Vicens-Caldentey, Caterina
Domínguez-García, Marta
Bartolomé-Moreno, Cruz
Recio-Rodriguez, Jose I
Bellón, Juan Á
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv
dc.subject.none.fl_str_mv Ejercicio Físico
Trastorno Depresivo Mayor
Humanos
Depresión
Conductas Relacionadas con la Salud
Health Behavior
Depressive Disorder, Major
Humans
Depression
Exercise
topic Ejercicio Físico
Trastorno Depresivo Mayor
Humanos
Depresión
Conductas Relacionadas con la Salud
Health Behavior
Depressive Disorder, Major
Humans
Depression
Exercise
description Objective: To examine the effectiveness of a 12-month MHBC intervention in the prevention of onset depression in primary health care (PHC). Methods: Twenty-two PHC centres took part in the cluster-randomized controlled trial. Patients were randomized to receive either usual care or an MHBC intervention. The endpoints were onset of major depression and reduction of depressive symptoms in participants without baseline depression at a 12-month follow-up. Results: 2531 patients agreed and were eligible to participate. At baseline, around 43% were smokers, 82% were non-adherent to the Mediterranean diet and 55% did not perform enough physical activity. The intervention group exhibited a greater positive change in two or more behaviours (OR 1.75 [95%CI: 1.17 to 2.62]; p = 0.006); any behaviour (OR 1.58 [95%CI: 1.13 to 2.20]; p = 0.007); and adherence to the Mediterranean diet (OR 1.94 [95%CI: 1.29 to 2.94]; p = 0.002), while this increase was not statistically significant for smoking and physical activity. The intervention was not effective in preventing major depression (OR 1.17; [95% CI 0.53 to 2.59)]; p = 0.690) or reducing depressive symptoms (Mean difference: 0.30; [95% CI -0.77 to 1.36]; p = 0.726) during follow-up. Conclusions: As compared to usual care, the MHBC intervention provided a non-significant reduction in the incidence of major depression. Trial registration: ClinicalTrials.gov, NCT03136211.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-01-01
2023
2023-01-01
2024
2024-10-09
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/20.500.12105/23573
url https://hdl.handle.net/20.500.12105/23573
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repisalud
instname:Instituto de Salud Carlos III (ISCIII)
instname_str Instituto de Salud Carlos III (ISCIII)
reponame_str Repisalud
collection Repisalud
repository.name.fl_str_mv
repository.mail.fl_str_mv
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