Short-Term Panax Ginseng Extract Supplementation Reduces Fasting Blood Triacylglycerides and Oxygen Consumption during Sub-Maximal Aerobic Exercise in Male Recreational Athletes

Ginseng, a popular herbal supplement among athletes, is believed to enhance exercise capacity and performance. This study investigated the short-term effects of Panax ginseng extract (PG) on aerobic capacity, lipid profile, and cytokines. In a 14-day randomized, double-blind trial, male participants...

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Detalhes bibliográficos
Autores: Hernández García, Cristian Didier, Granado-Serrano, Ana Belén, Martín Garí, Meritxell, Ensenyat Solé, Assumpta, Naudí i Farré, Alba, Serrano Casasola, José Carlos Enrique
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Recursos:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/465876
Acesso em linha:https://doi.org/10.3390/biom14050533
https://hdl.handle.net/10459.1/465876
Access Level:acceso abierto
Palavra-chave:Sub-maximal aerobic capacity
Endurance
Blood lipids
Panax ginseng
Recreational athletes
Descrição
Resumo:Ginseng, a popular herbal supplement among athletes, is believed to enhance exercise capacity and performance. This study investigated the short-term effects of Panax ginseng extract (PG) on aerobic capacity, lipid profile, and cytokines. In a 14-day randomized, double-blind trial, male participants took 500 mg of PG daily. Two experiments were conducted: one in 10 km races (n = 31) and another in a laboratory-controlled aerobic capacity test (n = 20). Blood lipid and cytokine profile, ventilation, oxygen consumption, hemodynamic and fatigue parameters, and race time were evaluated. PG supplementation led to reduced total blood lipid levels, particularly in triacylglycerides (10 km races −7.5 mg/dL (95% CI −42 to 28); sub-maximal aerobic test −14.2 mg/dL (95% CI −52 to 23)), while post-exercise blood IL-10 levels were increased (10 km 34.0 pg/mL (95% CI −2.1 to 70.1); sub-maximal aerobic test 4.1 pg/mL (95% CI −2.8 to 11.0)), and oxygen consumption decreased during the sub-maximal aerobic test (VO2: −1.4 mL/min/kg (95% CI −5.8 to −0.6)). No significant differences were noted in race time, hemodynamic, or fatigue parameters. Overall, PG supplementation for 2 weeks showed benefits in blood lipid profile and energy consumption during exercise among recreational athletes. This suggests a potential role for PG in enhancing exercise performance and metabolic health in this population.