Organocatalysis on Tap: Enantioselective Continuous Flow Processes Mediated by Solid-Supported Chiral Organocatalysts
<p style="text-align: justify;"> Sustainability concerns are reshaping the way chemists work, not only at the stage of process design, but also when actually performing reactions. This change of paradigm is exemplified by the deployment of continuous flow techniques, which are slowly...
| Autores: | , |
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| Formato: | artículo |
| Fecha de publicación: | 2015 |
| País: | España |
| Recursos: | Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya) |
| Repositorio: | Recercat. Dipósit de la Recerca de Catalunya |
| OAI Identifier: | oai:recercat.cat:2072/305808 |
| Acesso em linha: | http://hdl.handle.net/2072/305808 https://doi.org/10.1002/ejoc.201403042 |
| Access Level: | acceso abierto |
| Palavra-chave: | Continuous flow chemistry Supported catalysts Asymmetric catalysis Organocatalysis Sustainable chemistry |
| Resumo: | <p style="text-align: justify;"> Sustainability concerns are reshaping the way chemists work, not only at the stage of process design, but also when actually performing reactions. This change of paradigm is exemplified by the deployment of continuous flow techniques, which are slowly becoming a mainstream practice. Indeed, the possibility of performing catalytic processes (the flagship of sustainable chemistry) in flow presents distinctive advantages. Thus, several authors are focusing their efforts in trying to get the best of these two worlds, with the consequent challenge of finding common solutions for their respective issues. In the last years, this approach has been taken one step further with the use in flow processing of enantioselective organocatalysts, which allow the production of enantiopure compounds free of metal contaminants. Herein, we will cover the literature concerning the use of solid-supported organocatalysts for the continuous flow production of enantiomerically enriched compounds.</p> |
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