Opportunistic Community Screening of Chronic Chagas Disease Using a Rapid Diagnosis Test in Pharmacies in Barcelona (Catalonia, Spain)

This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed...

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Detalhes bibliográficos
Autores: Silgado, Aroa|||0000-0001-7581-0049, Bosch-Nicolau, Pau|||0000-0002-7435-1829, Sánchez Montalvá, Adrián|||0000-0002-2194-5447, Cervià, Ariadna, Gómez i Prat, Jordi|||0000-0001-7041-9526, Bagaria, Guillermo, Rodríguez, Cristina|||0000-0002-6472-5647, Goterris, Lidia|||0000-0003-1471-4461, Serre-Delcor, Núria|||0000-0001-5984-4185, Oliveira, Ines|||0000-0001-6018-5797, Salvador Velez, Fernando Maria|||0000-0002-0546-1354, Molina Romero, Israel|||0000-0001-6642-7515, Sulleiro, Elena|||0000-0002-9783-6060
Formato: artículo
Fecha de publicación:2022
País:España
Recursos:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:281751
Acesso em linha:https://ddd.uab.cat/record/281751
https://dx.doi.org/urn:doi:10.3389/ijph.2022.1605386
Access Level:acceso abierto
Palavra-chave:Chagas disease
Community pharmacies
Dried blood
Opportunistic screening
Rapid test
Descrição
Resumo:This study aimed to report the protocol and results from the pilot phase of an opportunistic CP-based CD screening program in Barcelona, Spain. Three strategies according to recruitment approach were designed: passive, active and active-community. The study process consisted of signing the informed consent form, recording the patient's data in a web-based database system, and performing the rapid test and blood collection on dry paper. Nineteen pharmacies participated and 64 patients were included during the pilot phase of the study. The rapid diagnostic test (RDT) was positive in 2/64 (3.13%) cases. Of the 49 DBS samples that arrived at the laboratory, 22 (45%) were collected incorrectly. After quantitative and qualitative assessment of the program, the dry paper sample and passive strategy were ruled out. DBS sampling and the passive strategy are not suitable for CD screening in community pharmacies. There is a need to expand the number of participating pharmacies and individuals to determine whether conducting a RDT in community pharmacies is an effective screening method to increase access to CD diagnosis in a non-endemic area.

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