Sleeve gastrectomy in patients with severe obesity restores circadian rhythms and their relationship with sleep pattern
Advances in research have linked alterations of circadian rhythms with obesity. However, few</p><p>studies have focused on the recovery of the circadian expression after a weight loss treatment.</p><p>Our aim was to study the alterations of the circadian rhythmicity due to mo...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2021 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/225947 |
| Acceso en línea: | https://hdl.handle.net/2445/225947 |
| Access Level: | acceso abierto |
| Palabra clave: | Obesitat Ritmes circadiaris Cirurgia Obesity Circadian rhythms Surgery |
| Sumario: | Advances in research have linked alterations of circadian rhythms with obesity. However, few</p><p>studies have focused on the recovery of the circadian expression after a weight loss treatment.</p><p>Our aim was to study the alterations of the circadian rhythmicity due to morbid obesity and the</p><p>recovery of the circadian pattern after weight loss in a cohort of patients who underwent sleeve</p><p>gastrectomy. For this purpose, 41 patients with severe obesity (75% women; age [mean (SD)]</p><p>49.7 ± 10 years; BMI 44.3 ± 6.2 kg/m2) were monitored before bariatric surgery and 9 months</p><p>afterward. On both occasions, activity and wrist temperature were determined by actigraphy and</p><p>were related with weight loss. Anthropometric, biochemical, and sleep-related variables, along with</p><p>dietary intake and physical activity, were analyzed in relation with circadian rhythmicity. Results</p><p>show significant differences in the circadian expression before and after 9 months of bariatric</p><p>surgery, with more stable and less fragmented rhythms after weight loss. Moreover, only after</p><p>surgery were the circadian variables associated to sleep timing and chronotype. The findings of this</p><p>study indicate that weight loss treatment in patients with morbid obesity improves the circadian</p><p>rhythm expression, and in such a way that it could be associated with better sleep quality.</p><p>Moreover, it allows the recovery of the relationship between sleep patterns and circadian rhythm</p><p>that was lost due to the obesity. |
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