Predicting Dimensions in Microfluidic Paper Based Analytical Devices

The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable mi...

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Autores: Catalán Carrio, Raquel, Akyazi, Tugce, Basabe Desmonts, Lourdes, Benito López, Fernando
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/49745
Acceso en línea:http://hdl.handle.net/10810/49745
Access Level:acceso abierto
Palabra clave:LOC
wax printing
paper microfluidics
µPAD
paper microfluidics fabrication
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spelling Predicting Dimensions in Microfluidic Paper Based Analytical DevicesCatalán Carrio, RaquelAkyazi, TugceBasabe Desmonts, LourdesBenito López, FernandoLOCwax printingpaper microfluidicsµPADpaper microfluidics fabricationThe main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner.The authors would like to acknowledge funding support from Gobierno de España, Ministerio de Economía y Competitividad, with Grant No. BIO2016-80417-P (AEI/FEDER, UE), the Gobierno Vasco Dpto. Educación for the consolidation of the research groups (IT1271-19) and from Proyectos Colaborativos from the University of the Basque Country UPV/EHU, BIOPLASMOF (COLAB19/05). This project received funding from the European Union’s Horizon 2020 research and innovation programme under the Marie Skłodowska-Curie grant agreement No. 778001.MDPI2021202120202021info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/49745reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoInglésinfo:eu-repo/grantAgreement/MINECO/ BIO2016-80417-P/info:eu-repo/grantAgreement/EC/H2020/778001https://www.mdpi.com/1424-8220/21/1/101/htminfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/es/2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).oai:addi.ehu.eus:10810/497452026-06-18T09:23:17Z
dc.title.none.fl_str_mv Predicting Dimensions in Microfluidic Paper Based Analytical Devices
title Predicting Dimensions in Microfluidic Paper Based Analytical Devices
spellingShingle Predicting Dimensions in Microfluidic Paper Based Analytical Devices
Catalán Carrio, Raquel
LOC
wax printing
paper microfluidics
µPAD
paper microfluidics fabrication
title_short Predicting Dimensions in Microfluidic Paper Based Analytical Devices
title_full Predicting Dimensions in Microfluidic Paper Based Analytical Devices
title_fullStr Predicting Dimensions in Microfluidic Paper Based Analytical Devices
title_full_unstemmed Predicting Dimensions in Microfluidic Paper Based Analytical Devices
title_sort Predicting Dimensions in Microfluidic Paper Based Analytical Devices
dc.creator.none.fl_str_mv Catalán Carrio, Raquel
Akyazi, Tugce
Basabe Desmonts, Lourdes
Benito López, Fernando
author Catalán Carrio, Raquel
author_facet Catalán Carrio, Raquel
Akyazi, Tugce
Basabe Desmonts, Lourdes
Benito López, Fernando
author_role author
author2 Akyazi, Tugce
Basabe Desmonts, Lourdes
Benito López, Fernando
author2_role author
author
author
dc.subject.none.fl_str_mv LOC
wax printing
paper microfluidics
µPAD
paper microfluidics fabrication
topic LOC
wax printing
paper microfluidics
µPAD
paper microfluidics fabrication
description The main problem for the expansion of the use of microfluidic paper-based analytical devices and, thus, their mass production is their inherent lack of fluid flow control due to its uncontrolled fabrication protocols. To address this issue, the first step is the generation of uniform and reliable microfluidic channels. The most common paper microfluidic fabrication method is wax printing, which consists of two parts, printing and heating, where heating is a critical step for the fabrication of reproducible device dimensions. In order to bring paper-based devices to success, it is essential to optimize the fabrication process in order to always get a reproducible device. Therefore, the optimization of the heating process and the analysis of the parameters that could affect the final dimensions of the device, such as its shape, the width of the wax barrier and the internal area of the device, were performed. Moreover, we present a method to predict reproducible devices with controlled working areas in a simple manner.
publishDate 2020
dc.date.none.fl_str_mv 2020
2021
2021
2021
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/49745
url http://hdl.handle.net/10810/49745
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/MINECO/ BIO2016-80417-P/
info:eu-repo/grantAgreement/EC/H2020/778001
https://www.mdpi.com/1424-8220/21/1/101/htm
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/es/
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
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dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
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