Phenolic Composition, Antioxidant Capacity and Antiproliferative Activity of Ten Exotic Amazonian fruit

The socioeconomic, cultural, therapeutic, and nutritional potential of Amazonian fruits has been limited due to the scarce information about its phytochemical profile. The aim of this study was to determine the total phenolic content profiles by Folin colorimetric miniaturized assay, the identificat...

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Detalhes bibliográficos
Autores: Becker, Magda Márcia, Gaëlle Catanantea, Gaëlle, Mármol, Inés, Rodríguez Yoldi, Maria Jesús, Mishrad, Rupesh K., Barbosa, Sergio, Núñez Burcio, Oscar, Silva Nunes, Gilvanda, Marty, Jean-Louis
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:España
Recursos:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/158540
Acesso em linha:https://hdl.handle.net/2445/158540
Access Level:acceso abierto
Palavra-chave:Pebrots
Cromatografia de líquids d'alta resolució
Quimiometria
Química dels aliments
Peppers
High performance liquid chromatography
Chemometrics
Food composition
Descrição
Resumo:The socioeconomic, cultural, therapeutic, and nutritional potential of Amazonian fruits has been limited due to the scarce information about its phytochemical profile. The aim of this study was to determine the total phenolic content profiles by Folin colorimetric miniaturized assay, the identification of phenolic compounds by UHPLC-HRMS, the antioxidant capacity by DPPH, ABTS, and NBT assays, as well as, the antiproliferative activity by sulforhodamine B assay of extracts obtained from ten native fruits to the Amazon region, some of these consumed especially by indigenous population. A strong positive correlation between the content of total phenolic compounds and antioxidant capacity was demonstrated. The antiproliferative activities against Caco-2 cell line didn't necessarily be associated with a high antioxidant capacity and the total phenolic concentration, possibly, qualitative and quantitative differences in phenolic composition of these fruits influenced the antiproliferative activities. This research presented, for the first time, important characteristics of Amazon exotic fruits.