Rationale, design and organization of the delayed antibiotic prescription (DAP) trial

Poza Abad, Mariam de la|||0000-0001-5993-1596; Mas Dalmau, Gemma|||0000-0003-3720-0797; Moreno Bakedano, Mikel; González González, Ana Isabel|||0000-0001-7167-4211; Canellas Criado, Yolanda; Hernández Anadón, Silvia; Rotaeche Del Campo, Rafael; Torán-Monserrat, Pere|||0000-0002-9865-7427; Negrete Palma, Antonio; Pera, Guillem|||0000-0003-3188-7268; Borrell-Thió, Eulàlia; Llor, Carl|||0000-0001-6644-717X; Little, Paul|||0000-0003-3664-1873; Alonso-Coello, Pablo|||0000-0002-8001-8504

Rationale, design and organization of the delayed antibiotic prescription (DAP) trial

Background: Respiratory tract infections are an important burden in primary care and it's known that they are usually self-limited and that antibiotics only alter its course slightly. This together with the alarming increase of bacterial resistance due to increased use of antimicrobials calls f...

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Autores:	Poza Abad, Mariam de la\|\|\|0000-0001-5993-1596, Mas Dalmau, Gemma\|\|\|0000-0003-3720-0797, Moreno Bakedano, Mikel, González González, Ana Isabel\|\|\|0000-0001-7167-4211, Canellas Criado, Yolanda, Hernández Anadón, Silvia, Rotaeche Del Campo, Rafael, Torán-Monserrat, Pere\|\|\|0000-0002-9865-7427, Negrete Palma, Antonio, Pera, Guillem\|\|\|0000-0003-3188-7268, Borrell-Thió, Eulàlia, Llor, Carl\|\|\|0000-0001-6644-717X, Little, Paul\|\|\|0000-0003-3664-1873, Alonso-Coello, Pablo\|\|\|0000-0002-8001-8504
Tipo de recurso:	artículo
Fecha de publicación:	2013
País:	España
Institución:	Universitat Autònoma de Barcelona
Repositorio:	Dipòsit Digital de Documents de la UAB
Idioma:	inglés
OAI Identifier:	oai:ddd.uab.cat:303807
Acceso en línea:	https://ddd.uab.cat/record/303807 https://dx.doi.org/urn:doi:10.1186/1471-2296-14-63
Access Level:	acceso abierto
Palabra clave:	Acute bronchitis Acute tonsillitis Chronic obstructive pulmonary disease Delayed antibiotic prescription Family medicine Pharyngitis Respiratory infections Rhinosinusitis

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spelling	Rationale, design and organization of the delayed antibiotic prescription (DAP) trialA randomized controlled trial of the efficacy and safety of delayed antibiotic prescribing strategies in the non-complicated acute respiratory tract infections in general practicePoza Abad, Mariam de la\|\|\|0000-0001-5993-1596Mas Dalmau, Gemma\|\|\|0000-0003-3720-0797Moreno Bakedano, MikelGonzález González, Ana Isabel\|\|\|0000-0001-7167-4211Canellas Criado, YolandaHernández Anadón, SilviaRotaeche Del Campo, RafaelTorán-Monserrat, Pere\|\|\|0000-0002-9865-7427Negrete Palma, AntonioPera, Guillem\|\|\|0000-0003-3188-7268Borrell-Thió, EulàliaLlor, Carl\|\|\|0000-0001-6644-717XLittle, Paul\|\|\|0000-0003-3664-1873Alonso-Coello, Pablo\|\|\|0000-0002-8001-8504Acute bronchitisAcute tonsillitisChronic obstructive pulmonary diseaseDelayed antibiotic prescriptionFamily medicinePharyngitisRespiratory infectionsRhinosinusitisBackground: Respiratory tract infections are an important burden in primary care and it's known that they are usually self-limited and that antibiotics only alter its course slightly. This together with the alarming increase of bacterial resistance due to increased use of antimicrobials calls for a need to consider strategies to reduce their use. One of these strategies is the delayed prescription of antibiotics. Methods. Multicentric, parallel, randomised controlled trial comparing four antibiotic prescribing strategies in acute non-complicated respiratory tract infections. We will include acute pharyngitis, rhinosinusitis, acute bronchitis and acute exacerbation of chronic bronchitis or chronic obstructive pulmonary disease (mild to moderate). The therapeutic strategies compared are: immediate antibiotic treatment, no antibiotic treatment, and two delayed antibiotic prescribing (DAP) strategies with structured advice to use a course of antibiotics in case of worsening of symptoms or not improving (prescription given to patient or prescription left at the reception of the primary care centre 3 days after the first medical visit). Discussion. Delayed antibiotic prescription has been widely used in Anglo-Saxon countries, however, in Southern Europe there has been little research about this topic. The DAP trial wil evaluate two different delayed strategies in Spain for the main respiratory infections in primary care. Trial registration. This trial is registered with ClinicalTrials.gov, number. © 2013 de la Poza Abad et al.; licensee BioMed Central Ltd.Universitat Autònoma de Barcelona 22013-01-0120132013-01-01Articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://ddd.uab.cat/record/303807https://dx.doi.org/urn:doi:10.1186/1471-2296-14-63reponame:Dipòsit Digital de Documents de la UABinstname:Universitat Autònoma de BarcelonaInglésengopen accesshttp://purl.org/coar/access_right/c_abf2Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.https://creativecommons.org/licenses/by/2.0/info:eu-repo/semantics/openAccessoai:ddd.uab.cat:3038072026-06-06T12:50:31Z
dc.title.none.fl_str_mv	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial A randomized controlled trial of the efficacy and safety of delayed antibiotic prescribing strategies in the non-complicated acute respiratory tract infections in general practice
title	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
spellingShingle	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial Poza Abad, Mariam de la\|\|\|0000-0001-5993-1596 Acute bronchitis Acute tonsillitis Chronic obstructive pulmonary disease Delayed antibiotic prescription Family medicine Pharyngitis Respiratory infections Rhinosinusitis
title_short	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
title_full	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
title_fullStr	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
title_full_unstemmed	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
title_sort	Rationale, design and organization of the delayed antibiotic prescription (DAP) trial
dc.creator.none.fl_str_mv	Poza Abad, Mariam de la\|\|\|0000-0001-5993-1596 Mas Dalmau, Gemma\|\|\|0000-0003-3720-0797 Moreno Bakedano, Mikel González González, Ana Isabel\|\|\|0000-0001-7167-4211 Canellas Criado, Yolanda Hernández Anadón, Silvia Rotaeche Del Campo, Rafael Torán-Monserrat, Pere\|\|\|0000-0002-9865-7427 Negrete Palma, Antonio Pera, Guillem\|\|\|0000-0003-3188-7268 Borrell-Thió, Eulàlia Llor, Carl\|\|\|0000-0001-6644-717X Little, Paul\|\|\|0000-0003-3664-1873 Alonso-Coello, Pablo\|\|\|0000-0002-8001-8504
author	Poza Abad, Mariam de la\|\|\|0000-0001-5993-1596
author_facet	Poza Abad, Mariam de la\|\|\|0000-0001-5993-1596 Mas Dalmau, Gemma\|\|\|0000-0003-3720-0797 Moreno Bakedano, Mikel González González, Ana Isabel\|\|\|0000-0001-7167-4211 Canellas Criado, Yolanda Hernández Anadón, Silvia Rotaeche Del Campo, Rafael Torán-Monserrat, Pere\|\|\|0000-0002-9865-7427 Negrete Palma, Antonio Pera, Guillem\|\|\|0000-0003-3188-7268 Borrell-Thió, Eulàlia Llor, Carl\|\|\|0000-0001-6644-717X Little, Paul\|\|\|0000-0003-3664-1873 Alonso-Coello, Pablo\|\|\|0000-0002-8001-8504
author_role	author
author2	Mas Dalmau, Gemma\|\|\|0000-0003-3720-0797 Moreno Bakedano, Mikel González González, Ana Isabel\|\|\|0000-0001-7167-4211 Canellas Criado, Yolanda Hernández Anadón, Silvia Rotaeche Del Campo, Rafael Torán-Monserrat, Pere\|\|\|0000-0002-9865-7427 Negrete Palma, Antonio Pera, Guillem\|\|\|0000-0003-3188-7268 Borrell-Thió, Eulàlia Llor, Carl\|\|\|0000-0001-6644-717X Little, Paul\|\|\|0000-0003-3664-1873 Alonso-Coello, Pablo\|\|\|0000-0002-8001-8504
author2_role	author author author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Universitat Autònoma de Barcelona
dc.subject.none.fl_str_mv	Acute bronchitis Acute tonsillitis Chronic obstructive pulmonary disease Delayed antibiotic prescription Family medicine Pharyngitis Respiratory infections Rhinosinusitis
topic	Acute bronchitis Acute tonsillitis Chronic obstructive pulmonary disease Delayed antibiotic prescription Family medicine Pharyngitis Respiratory infections Rhinosinusitis
description	Background: Respiratory tract infections are an important burden in primary care and it's known that they are usually self-limited and that antibiotics only alter its course slightly. This together with the alarming increase of bacterial resistance due to increased use of antimicrobials calls for a need to consider strategies to reduce their use. One of these strategies is the delayed prescription of antibiotics. Methods. Multicentric, parallel, randomised controlled trial comparing four antibiotic prescribing strategies in acute non-complicated respiratory tract infections. We will include acute pharyngitis, rhinosinusitis, acute bronchitis and acute exacerbation of chronic bronchitis or chronic obstructive pulmonary disease (mild to moderate). The therapeutic strategies compared are: immediate antibiotic treatment, no antibiotic treatment, and two delayed antibiotic prescribing (DAP) strategies with structured advice to use a course of antibiotics in case of worsening of symptoms or not improving (prescription given to patient or prescription left at the reception of the primary care centre 3 days after the first medical visit). Discussion. Delayed antibiotic prescription has been widely used in Anglo-Saxon countries, however, in Southern Europe there has been little research about this topic. The DAP trial wil evaluate two different delayed strategies in Spain for the main respiratory infections in primary care. Trial registration. This trial is registered with ClinicalTrials.gov, number. © 2013 de la Poza Abad et al.; licensee BioMed Central Ltd.
publishDate	2013
dc.date.none.fl_str_mv	2 2013-01-01 2013 2013-01-01
dc.type.none.fl_str_mv	Article http://purl.org/coar/resource_type/c_6501 VoR http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv	info:eu-repo/semantics/article
format	article
dc.identifier.none.fl_str_mv	https://ddd.uab.cat/record/303807 https://dx.doi.org/urn:doi:10.1186/1471-2296-14-63
url	https://ddd.uab.cat/record/303807 https://dx.doi.org/urn:doi:10.1186/1471-2296-14-63
dc.language.none.fl_str_mv	Inglés eng
language_invalid_str_mv	Inglés
language	eng
dc.rights.none.fl_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/2.0/
dc.rights.openaire.fl_str_mv	info:eu-repo/semantics/openAccess
rights_invalid_str_mv	open access http://purl.org/coar/access_right/c_abf2 https://creativecommons.org/licenses/by/2.0/
eu_rights_str_mv	openAccess
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dc.source.none.fl_str_mv	reponame:Dipòsit Digital de Documents de la UAB instname:Universitat Autònoma de Barcelona
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Rationale, design and organization of the delayed antibiotic prescription (DAP) trial

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