Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study

Appendiceal tumors represent a large amalgam of different tumor lineages. The continuous evolution in their pathological classifications has led to some variable recommended attitudes over time. The aim of this study is to review the incidence, clinicopathological characteristics, therapeutic approa...

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Autores: Gómez-Báez, Ferney David, Cerdán Santacruz, Carlos, Moreno Muguiro, Naroa, Milla Collado, Lucía, Merichal Resina, Mireia, Tarragona Foradada, Jordi, Sierra Grañón, Enrique, Olsina Kissler, Jorge Juan
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Universitat de Lleida (UdL)
Repositorio:Repositori Obert UdL
OAI Identifier:oai:repositori.udl.cat:10459.1/465897
Acceso en línea:https://doi.org/10.3390/gidisord5040037
https://hdl.handle.net/10459.1/465897
Access Level:acceso abierto
Palabra clave:Appendiceal neoplasms
Carcinoid tumor
Appendectomy
Low-grade appendiceal mucinous neoplasms
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spelling Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort StudyGómez-Báez, Ferney DavidCerdán Santacruz, CarlosMoreno Muguiro, NaroaMilla Collado, LucíaMerichal Resina, MireiaTarragona Foradada, JordiSierra Grañón, EnriqueOlsina Kissler, Jorge JuanAppendiceal neoplasmsCarcinoid tumorAppendectomyLow-grade appendiceal mucinous neoplasmsAppendiceal tumors represent a large amalgam of different tumor lineages. The continuous evolution in their pathological classifications has led to some variable recommended attitudes over time. The aim of this study is to review the incidence, clinicopathological characteristics, therapeutic approach and oncological results in this type of tumor at our institution. This is a single centre retrospective cohort study. Every pathologic report catalogued as an appendiceal specimen was reviewed for a time period of 5 years (2013–2017) at our institution. Demographic, clinical, pathological and oncologic follow-up data were recorded. A descriptive study of the sample was completed. A total of 1434 appendiceal specimens was analyzed. Appendiceal neoplasms incidence was 3.2%. Epithelial tumors were the predominant histological subtype, making up 68% of the cases. Low-grade appendiceal mucinous neoplasia and neuroendocrine tumors were the most frequent neoplasms with malignant potential, with 13 and 6 cases, respectively. In more than 80% of neoplasia cases, the definitive treatment was appendectomy. Mortality cases were related to tumors with a very poor prognosis and an advanced stage. All patients had adequate oncological follow-up. Although it is still quite rare, the incidence of appendiceal tumors is increasing with an epidemiological change in favor of mucinous neoplasms currently predominating. Therefore, it is necessary to know and use an updated anatomo-pathological classification in order to provide correct treatment in the first or second surgical stage, as well as the correct follow-up of patientsMDPI2023info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://doi.org/10.3390/gidisord5040037https://hdl.handle.net/10459.1/465897reponame:Repositori Obert UdL instname:Universitat de Lleida (UdL)InglésReproducció del document publicat a: https://doi.org/10.3390/gidisord5040037Gastrointestinal Disorders, 2023, vol. 5, núm. 4, p. 455-463cc-by (c) autors, 2023Attribution 4.0 Internationalinfo:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/4.0/oai:repositori.udl.cat:10459.1/4658972026-06-24T12:42:17Z
dc.title.none.fl_str_mv Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
title Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
spellingShingle Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
Gómez-Báez, Ferney David
Appendiceal neoplasms
Carcinoid tumor
Appendectomy
Low-grade appendiceal mucinous neoplasms
title_short Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
title_full Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
title_fullStr Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
title_full_unstemmed Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
title_sort Incidence, Clinicopathological Features and Oncologic Outcome of Appendiceal Neoplasms: A Single-Center Cohort Study
dc.creator.none.fl_str_mv Gómez-Báez, Ferney David
Cerdán Santacruz, Carlos
Moreno Muguiro, Naroa
Milla Collado, Lucía
Merichal Resina, Mireia
Tarragona Foradada, Jordi
Sierra Grañón, Enrique
Olsina Kissler, Jorge Juan
author Gómez-Báez, Ferney David
author_facet Gómez-Báez, Ferney David
Cerdán Santacruz, Carlos
Moreno Muguiro, Naroa
Milla Collado, Lucía
Merichal Resina, Mireia
Tarragona Foradada, Jordi
Sierra Grañón, Enrique
Olsina Kissler, Jorge Juan
author_role author
author2 Cerdán Santacruz, Carlos
Moreno Muguiro, Naroa
Milla Collado, Lucía
Merichal Resina, Mireia
Tarragona Foradada, Jordi
Sierra Grañón, Enrique
Olsina Kissler, Jorge Juan
author2_role author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Appendiceal neoplasms
Carcinoid tumor
Appendectomy
Low-grade appendiceal mucinous neoplasms
topic Appendiceal neoplasms
Carcinoid tumor
Appendectomy
Low-grade appendiceal mucinous neoplasms
description Appendiceal tumors represent a large amalgam of different tumor lineages. The continuous evolution in their pathological classifications has led to some variable recommended attitudes over time. The aim of this study is to review the incidence, clinicopathological characteristics, therapeutic approach and oncological results in this type of tumor at our institution. This is a single centre retrospective cohort study. Every pathologic report catalogued as an appendiceal specimen was reviewed for a time period of 5 years (2013–2017) at our institution. Demographic, clinical, pathological and oncologic follow-up data were recorded. A descriptive study of the sample was completed. A total of 1434 appendiceal specimens was analyzed. Appendiceal neoplasms incidence was 3.2%. Epithelial tumors were the predominant histological subtype, making up 68% of the cases. Low-grade appendiceal mucinous neoplasia and neuroendocrine tumors were the most frequent neoplasms with malignant potential, with 13 and 6 cases, respectively. In more than 80% of neoplasia cases, the definitive treatment was appendectomy. Mortality cases were related to tumors with a very poor prognosis and an advanced stage. All patients had adequate oncological follow-up. Although it is still quite rare, the incidence of appendiceal tumors is increasing with an epidemiological change in favor of mucinous neoplasms currently predominating. Therefore, it is necessary to know and use an updated anatomo-pathological classification in order to provide correct treatment in the first or second surgical stage, as well as the correct follow-up of patients
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3390/gidisord5040037
https://hdl.handle.net/10459.1/465897
url https://doi.org/10.3390/gidisord5040037
https://hdl.handle.net/10459.1/465897
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/gidisord5040037
Gastrointestinal Disorders, 2023, vol. 5, núm. 4, p. 455-463
dc.rights.none.fl_str_mv cc-by (c) autors, 2023
Attribution 4.0 International
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/4.0/
rights_invalid_str_mv cc-by (c) autors, 2023
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositori Obert UdL
instname:Universitat de Lleida (UdL)
instname_str Universitat de Lleida (UdL)
reponame_str Repositori Obert UdL
collection Repositori Obert UdL
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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