Prolonged QT Interval in SARS-CoV-2 Infection

Background: The prognostic value of a prolonged QT interval in SARS-Cov2 infection is not well known. Objective: To determine whether the presence of a prolonged QT on admission is an independent factor for mortality in SARS-Cov2 hospitalized patients. Methods: Single-center cohort of 623 consecutiv...

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Detalles Bibliográficos
Autores: Farré, Núria|||0000-0003-3110-6572, Mojón, Diana, Llagostera-Martín, Marc|||0000-0002-6211-7453, Belarte Tornero, Laia Carla|||0000-0003-2774-1290, Calvo-Fernández, Alicia|||0000-0001-6504-3528, Vallés, Ermengol, Negrete, Alejandro, García-Guimaraes, Marcos|||0000-0001-8509-6184, Bartolomé, Yolanda, Fernández-Aláez, Camino|||0000-0001-9385-1354, García-Duran, Ana B., Marrugat, Jaume|||0000-0003-3320-554X, Vaquerizo, Beatriz|||0000-0002-1428-3596
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:252868
Acceso en línea:https://ddd.uab.cat/record/252868
https://dx.doi.org/urn:doi:10.3390/jcm9092712
Access Level:acceso abierto
Palabra clave:QT interval
COVID-19
Hydroxychloroquine
Azithromycin
Prognosis
Death
Descripción
Sumario:Background: The prognostic value of a prolonged QT interval in SARS-Cov2 infection is not well known. Objective: To determine whether the presence of a prolonged QT on admission is an independent factor for mortality in SARS-Cov2 hospitalized patients. Methods: Single-center cohort of 623 consecutive patients with positive polymerase-chain-reaction test (PCR) to SARS Cov2, recruited from 27 February to 7 April 2020. An electrocardiogram was taken on these patients within the first 48 h after diagnosis and before the administration of any medication with a known effect on QT interval. A prolonged QT interval was defined as a corrected QT (QTc) interval.