Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery

Chronic pesticide poisoning is difficult to detect. We sought to develop a low-cost test battery for settings such as Ecuador’s floriculture industry. First we had to develop a case definition; as with all occupational diseases a case had to have both sufficient effective dose and associated health...

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Autores: Breilh Paz y Miño, Jaime Eduardo, Pagliccia, Nino, Yassi, Annalee
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2012
País:Ecuador
Institución:Universidad Andina Simón Bolivar
Repositorio:Repositorio Universidad Andina Simón Bolivar
Idioma:inglés
OAI Identifier:oai:repositorio.uasb.edu.ec:10644/3290
Acceso en línea:http://hdl.handle.net/10644/3290
Access Level:acceso abierto
Palabra clave:CONTAMINACIÓN POR PLAGUICIDAS
FLORICULTURA
TOXICOLOGÍA DE PLAGUICIDAS
PRUEBAS DE TOXICIDAD
TOXICOLOGÍA EXPERIMENTAL
NEUROBEHAVIOURAL EVALUATION SYSTEM, NES2
ENVIRONMENTAL STRESSORS
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spelling Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test batteryBreilh Paz y Miño, Jaime EduardoPagliccia, NinoYassi, AnnaleeCONTAMINACIÓN POR PLAGUICIDASFLORICULTURATOXICOLOGÍA DE PLAGUICIDASPRUEBAS DE TOXICIDADTOXICOLOGÍA EXPERIMENTALNEUROBEHAVIOURAL EVALUATION SYSTEM, NES2ENVIRONMENTAL STRESSORSChronic pesticide poisoning is difficult to detect. We sought to develop a low-cost test battery for settings such as Ecuador’s floriculture industry. First we had to develop a case definition; as with all occupational diseases a case had to have both sufficient effective dose and associated health effects. For the former, using canonical discriminant analysis, we found that adding measures of protection and overall environmental stressors to occupational category and duration of exposure was useful. For the latter, factor analysis suggested three distinct manifestations of pesticide poisoning. We then determined sensitivity and specificity of various combinations of symptoms and simple neurotoxicity tests from the Pentox questionnaire, and found that doing so increased sensitivity and specificity compared to use of acethylcholinesterase alone – the current screening standard. While sensitivity and specificity varied with different case definitions, our results support the development of a low-cost test battery for screening in such settings.W.S. Maney & Son2013-07-01T08:01:31Z2013-07-01T08:01:31Z2012info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfBreilh, Jaime; Pagliccia, Nino y Yassi, Annalee. Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery. International Journal of Occupational and Environmental Health, 2012, 18(1): 7-21.http://hdl.handle.net/10644/3290engECUADORCAYAMBEREGIÓN ANDINAhttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad Andina Simón Bolivarinstname:Universidad Andina Simón Bolivarinstacron:UASB2021-11-29T20:13:35Zoai:repositorio.uasb.edu.ec:10644/3290Institucionalhttps://repositorio.uasb.edu.ec/Institución privadahttps://www.uasb.edu.ec/https://repositorio.uasb.edu.ec/oai.Ecuador...opendoar:17692023-10-28T20:54:18.019742Repositorio Universidad Andina Simón Bolivar - Universidad Andina Simón Bolivartrue
dc.title.none.fl_str_mv Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
title Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
spellingShingle Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
Breilh Paz y Miño, Jaime Eduardo
CONTAMINACIÓN POR PLAGUICIDAS
FLORICULTURA
TOXICOLOGÍA DE PLAGUICIDAS
PRUEBAS DE TOXICIDAD
TOXICOLOGÍA EXPERIMENTAL
NEUROBEHAVIOURAL EVALUATION SYSTEM, NES2
ENVIRONMENTAL STRESSORS
title_short Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
title_full Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
title_fullStr Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
title_full_unstemmed Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
title_sort Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery
dc.creator.none.fl_str_mv Breilh Paz y Miño, Jaime Eduardo
Pagliccia, Nino
Yassi, Annalee
author Breilh Paz y Miño, Jaime Eduardo
author_facet Breilh Paz y Miño, Jaime Eduardo
Pagliccia, Nino
Yassi, Annalee
author_role author
author2 Pagliccia, Nino
Yassi, Annalee
author2_role author
author
dc.subject.none.fl_str_mv CONTAMINACIÓN POR PLAGUICIDAS
FLORICULTURA
TOXICOLOGÍA DE PLAGUICIDAS
PRUEBAS DE TOXICIDAD
TOXICOLOGÍA EXPERIMENTAL
NEUROBEHAVIOURAL EVALUATION SYSTEM, NES2
ENVIRONMENTAL STRESSORS
topic CONTAMINACIÓN POR PLAGUICIDAS
FLORICULTURA
TOXICOLOGÍA DE PLAGUICIDAS
PRUEBAS DE TOXICIDAD
TOXICOLOGÍA EXPERIMENTAL
NEUROBEHAVIOURAL EVALUATION SYSTEM, NES2
ENVIRONMENTAL STRESSORS
description Chronic pesticide poisoning is difficult to detect. We sought to develop a low-cost test battery for settings such as Ecuador’s floriculture industry. First we had to develop a case definition; as with all occupational diseases a case had to have both sufficient effective dose and associated health effects. For the former, using canonical discriminant analysis, we found that adding measures of protection and overall environmental stressors to occupational category and duration of exposure was useful. For the latter, factor analysis suggested three distinct manifestations of pesticide poisoning. We then determined sensitivity and specificity of various combinations of symptoms and simple neurotoxicity tests from the Pentox questionnaire, and found that doing so increased sensitivity and specificity compared to use of acethylcholinesterase alone – the current screening standard. While sensitivity and specificity varied with different case definitions, our results support the development of a low-cost test battery for screening in such settings.
publishDate 2012
dc.date.none.fl_str_mv 2012
2013-07-01T08:01:31Z
2013-07-01T08:01:31Z
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv Breilh, Jaime; Pagliccia, Nino y Yassi, Annalee. Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery. International Journal of Occupational and Environmental Health, 2012, 18(1): 7-21.
http://hdl.handle.net/10644/3290
identifier_str_mv Breilh, Jaime; Pagliccia, Nino y Yassi, Annalee. Chronic pesticide poisoning from persistent low-dose exposures in Ecuadorean floriculture workers: toward validating a low-cost test battery. International Journal of Occupational and Environmental Health, 2012, 18(1): 7-21.
url http://hdl.handle.net/10644/3290
dc.language.none.fl_str_mv eng
language eng
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by-nc-sa/3.0/ec/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-sa/3.0/ec/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.coverage.none.fl_str_mv ECUADOR
CAYAMBE
REGIÓN ANDINA
dc.publisher.none.fl_str_mv W.S. Maney & Son
publisher.none.fl_str_mv W.S. Maney & Son
dc.source.none.fl_str_mv reponame:Repositorio Universidad Andina Simón Bolivar
instname:Universidad Andina Simón Bolivar
instacron:UASB
instname_str Universidad Andina Simón Bolivar
instacron_str UASB
institution UASB
reponame_str Repositorio Universidad Andina Simón Bolivar
collection Repositorio Universidad Andina Simón Bolivar
repository.name.fl_str_mv Repositorio Universidad Andina Simón Bolivar - Universidad Andina Simón Bolivar
repository.mail.fl_str_mv .
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