Utilidad de la proteína C reactiva (PCR) como biomarcador temprano predictivo de sepsis en comparación con el marcador procaalcitonina (PCT) en los pacientes del northospital de la ciudad de Quito abril - junio del 2014.

In this study performed in the year 2014, it was proposed to determine the CRP as a predictive biomarker for sepsis compared with procalcitonina; patients with sepsis criteria were taken and compared using the ROC curve (Receiver Operating Characteristic) to determine a cohort point of CRP in all pa...

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Detalhes bibliográficos
Autor: Poma Valdivieso, José Rafael
Tipo de documento: dissertação
Estado:Versão publicada
Data de publicação:2015
País:Ecuador
Recursos:Universidad Nacional de Loja
Repositório:Repositorio Universidad Nacional de Loja
Idioma:espanhol
OAI Identifier:oai:dspace.unl.edu.ec:123456789/18933
Acesso em linha:http://dspace.unl.edu.ec/jspui/handle/123456789/18933
Access Level:Acceso aberto
Palavra-chave:BIOMARCADORES
SEPSIS
PROTEINA C REACTIVA
Descrição
Resumo:In this study performed in the year 2014, it was proposed to determine the CRP as a predictive biomarker for sepsis compared with procalcitonina; patients with sepsis criteria were taken and compared using the ROC curve (Receiver Operating Characteristic) to determine a cohort point of CRP in all patients with sepsis criteria and PCT indicating sepsis. In statistical, it was exposed that the cohort points obtained from the ROC curve, in the PCR it could be evaluated significant points 97 mg/L has a sensitivity of 58%, specificity of 57%, VPP 48 % and VPN 66 % and 181 mg/L has a sensitivity of 31%, and specificity of 78%, VPP 50% and VPN 62%. That is, the Procalcitonin is still the best biomarker for sepsis diagnosis, being PCR a biomarker of inflammation, which does not equal the PCT in diagnosing sepsis.