Neurocysticercosis: an update

Taeniosis and cysticercosis, diseases caused by the parasitic tapeworm Taenia solium, are distributed worldwide where pigs are eaten and sanitation is poor, and also in the more developed countries as a result of increasing migration. Neurocysticercosis is the commonest parasitic disease of the huma...

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Detalles Bibliográficos
Autor: Carpio, Arturo
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2002
País:Ecuador
Institución:Universidad de Cuenca
Repositorio:Repositorio Universidad de Cuenca
Idioma:inglés
OAI Identifier:oai:dspace.ucuenca.edu.ec:123456789/22196
Acceso en línea:http://dspace.ucuenca.edu.ec/handle/123456789/22196
Access Level:acceso abierto
Palabra clave:Neurocysticercosis
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spelling Neurocysticercosis: an updateLancet Infect DisCarpio, ArturoNeurocysticercosisTaeniosis and cysticercosis, diseases caused by the parasitic tapeworm Taenia solium, are distributed worldwide where pigs are eaten and sanitation is poor, and also in the more developed countries as a result of increasing migration. Neurocysticercosis is the commonest parasitic disease of the human nervous system. Immunological assays detect positivity for human cysticercosis in 8–12% of people in some endemic regions, which indicates the presence of antibodies against the parasite but not necessarily active or central-nervous-system infection. The only reliable tool for diagnosis of neurocysticercosis is imaging by CT or MRI. The presence of viable cysts with a mural nodule, associated with degenerative cysts and calcifications, is typical. Classification of neurocysticercosis into active, transitional, and inactive forms gives a good clinical-imaging correlation and facilitates medical and surgical treatment. The main clinical manifestations of neurocysticercosis are seizures, headache, and focal neurological deficits, and it can have such sequelae as epilepsy, hydrocephalus, and dementia. Treatment should be individually fitted for each patient, with antiepileptic drugs, analgesics, corticosteroids, or a combination of these. Anthelmintic drugs (praziquantel and albendazole) are used routinely, but so far no controlled clinical trial has established specific indications or definitive doses of treatment. Parenchymal forms of neurocysticercosis have a good prognosis in terms of clinical remission. The most effective approach to taeniosis and cysticercosis is prevention, which should be a primary public-health focus for less developed countriesvolumen 2; número 122015-06-15T15:58:43Z2015-06-15T15:58:43Z2002-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttp://dspace.ucuenca.edu.ec/handle/123456789/22196doi:10.1016/S1473-3099(02)00454-1enghttp://creativecommons.org/licenses/by-nc-sa/3.0/ec/info:eu-repo/semantics/openAccessreponame:Repositorio Universidad de Cuencainstname:Universidad de Cuencainstacron:UCUENCA2020-08-01T01:11:35Zoai:dspace.ucuenca.edu.ec:123456789/22196Institucionalhttp://dspace.ucuenca.edu.ec/Universidad públicahttps://www.ucuenca.edu.ec/http://dspace.ucuenca.edu.ec/oai.Ecuador...opendoar:41862020-08-01T01:11:35Repositorio Universidad de Cuenca - Universidad de Cuencafalse
dc.title.none.fl_str_mv Neurocysticercosis: an update
Lancet Infect Dis
title Neurocysticercosis: an update
spellingShingle Neurocysticercosis: an update
Carpio, Arturo
Neurocysticercosis
title_short Neurocysticercosis: an update
title_full Neurocysticercosis: an update
title_fullStr Neurocysticercosis: an update
title_full_unstemmed Neurocysticercosis: an update
title_sort Neurocysticercosis: an update
dc.creator.none.fl_str_mv Carpio, Arturo
author Carpio, Arturo
author_facet Carpio, Arturo
author_role author
dc.subject.none.fl_str_mv Neurocysticercosis
topic Neurocysticercosis
description Taeniosis and cysticercosis, diseases caused by the parasitic tapeworm Taenia solium, are distributed worldwide where pigs are eaten and sanitation is poor, and also in the more developed countries as a result of increasing migration. Neurocysticercosis is the commonest parasitic disease of the human nervous system. Immunological assays detect positivity for human cysticercosis in 8–12% of people in some endemic regions, which indicates the presence of antibodies against the parasite but not necessarily active or central-nervous-system infection. The only reliable tool for diagnosis of neurocysticercosis is imaging by CT or MRI. The presence of viable cysts with a mural nodule, associated with degenerative cysts and calcifications, is typical. Classification of neurocysticercosis into active, transitional, and inactive forms gives a good clinical-imaging correlation and facilitates medical and surgical treatment. The main clinical manifestations of neurocysticercosis are seizures, headache, and focal neurological deficits, and it can have such sequelae as epilepsy, hydrocephalus, and dementia. Treatment should be individually fitted for each patient, with antiepileptic drugs, analgesics, corticosteroids, or a combination of these. Anthelmintic drugs (praziquantel and albendazole) are used routinely, but so far no controlled clinical trial has established specific indications or definitive doses of treatment. Parenchymal forms of neurocysticercosis have a good prognosis in terms of clinical remission. The most effective approach to taeniosis and cysticercosis is prevention, which should be a primary public-health focus for less developed countries
publishDate 2002
dc.date.none.fl_str_mv 2002-12
2015-06-15T15:58:43Z
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