Fabrication of 3D bioactive ceramic scaffolds by robocasting

Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high repro...

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Detalles Bibliográficos
Autores: Andrade Cabrera, Santiago Patrico, Abdalla, A, Vanegas Peralta, Pablo Fernando
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Ecuador
Institución:Universidad de Cuenca
Repositorio:Repositorio Universidad de Cuenca
OAI Identifier:oai:dspace.ucuenca.edu.ec:123456789/22008
Acceso en línea:https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925256426&doi=10.1007%2f978-3-319-13117-7_44&partnerID=40&md5=67cd1475e1b87c8df6deea03624c1b61
http://dspace.ucuenca.edu.ec/handle/123456789/22008
Access Level:acceso abierto
Palabra clave:Biomaterials
Bioreactor
Bone Tissue Engineering
Flexible Scaffolds
Robocasting
Tricalcium Phosphate
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spelling Fabrication of 3D bioactive ceramic scaffolds by robocastingAndrade Cabrera, Santiago PatricoAbdalla, AVanegas Peralta, Pablo FernandoBiomaterialsBioreactorBone Tissue EngineeringFlexible ScaffoldsRobocastingTricalcium PhosphateTricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high reproducibility. Flexible composites are considered to promote mechano-biological stimulation during cell culture. The aim of this study is to fabricate flexible bioceramic scaffolds by robocasting and to determine biological improvements related to their added flexible properties. Characterized 3D ? - TCP/gelatin scaffolds with interconnected porous structure were fabricated using robocasting. SEM micrographs showed fabricated porous scaffolds with desired pore size (~200 ?m), rods diameter (~840 ?m), porosity and mechanical strength. Alamar Blue assay was performed for static and dynamic cultures along 21 days. Oscillatory flow conditions allowed considerable higher cell proliferation compared with static conditions.ParanáSPRINGER VERLAG2018-01-11T21:21:56Z2018-01-11T21:21:56Z2014-10-29info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdf978331913116016800737https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925256426&doi=10.1007%2f978-3-319-13117-7_44&partnerID=40&md5=67cd1475e1b87c8df6deea03624c1b61http://dspace.ucuenca.edu.ec/handle/123456789/2200810.1007/978-3-319-13117-7_44IFMBE Proceedingsreponame:Repositorio Universidad de Cuencainstname:Universidad de Cuencainstacron:UCUENCAen_USinfo:eu-repo/semantics/openAccess2020-08-01T01:16:30Zoai:dspace.ucuenca.edu.ec:123456789/22008Institucionalhttp://dspace.ucuenca.edu.ec/Universidad públicahttps://www.ucuenca.edu.ec/http://dspace.ucuenca.edu.ec/oai.Ecuador...opendoar:41862020-08-01T01:16:30Repositorio Universidad de Cuenca - Universidad de Cuencafalse
dc.title.none.fl_str_mv Fabrication of 3D bioactive ceramic scaffolds by robocasting
title Fabrication of 3D bioactive ceramic scaffolds by robocasting
spellingShingle Fabrication of 3D bioactive ceramic scaffolds by robocasting
Andrade Cabrera, Santiago Patrico
Biomaterials
Bioreactor
Bone Tissue Engineering
Flexible Scaffolds
Robocasting
Tricalcium Phosphate
title_short Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_full Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_fullStr Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_full_unstemmed Fabrication of 3D bioactive ceramic scaffolds by robocasting
title_sort Fabrication of 3D bioactive ceramic scaffolds by robocasting
dc.creator.none.fl_str_mv Andrade Cabrera, Santiago Patrico
Abdalla, A
Vanegas Peralta, Pablo Fernando
author Andrade Cabrera, Santiago Patrico
author_facet Andrade Cabrera, Santiago Patrico
Abdalla, A
Vanegas Peralta, Pablo Fernando
author_role author
author2 Abdalla, A
Vanegas Peralta, Pablo Fernando
author2_role author
author
dc.subject.none.fl_str_mv Biomaterials
Bioreactor
Bone Tissue Engineering
Flexible Scaffolds
Robocasting
Tricalcium Phosphate
topic Biomaterials
Bioreactor
Bone Tissue Engineering
Flexible Scaffolds
Robocasting
Tricalcium Phosphate
description Tricalcium phosphate ceramics are bioactive and osteoconductive biomaterials that support cellular functions and can develop appropriate mechanical characteristics for bone tissue engineering. Fast prototyping techniques permit to obtain accurate control over scaffolding architecture with high reproducibility. Flexible composites are considered to promote mechano-biological stimulation during cell culture. The aim of this study is to fabricate flexible bioceramic scaffolds by robocasting and to determine biological improvements related to their added flexible properties. Characterized 3D ? - TCP/gelatin scaffolds with interconnected porous structure were fabricated using robocasting. SEM micrographs showed fabricated porous scaffolds with desired pore size (~200 ?m), rods diameter (~840 ?m), porosity and mechanical strength. Alamar Blue assay was performed for static and dynamic cultures along 21 days. Oscillatory flow conditions allowed considerable higher cell proliferation compared with static conditions.
publishDate 2014
dc.date.none.fl_str_mv 2014-10-29
2018-01-11T21:21:56Z
2018-01-11T21:21:56Z
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv 9783319131160
16800737
https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925256426&doi=10.1007%2f978-3-319-13117-7_44&partnerID=40&md5=67cd1475e1b87c8df6deea03624c1b61
http://dspace.ucuenca.edu.ec/handle/123456789/22008
10.1007/978-3-319-13117-7_44
identifier_str_mv 9783319131160
16800737
10.1007/978-3-319-13117-7_44
url https://www.scopus.com/inward/record.uri?eid=2-s2.0-84925256426&doi=10.1007%2f978-3-319-13117-7_44&partnerID=40&md5=67cd1475e1b87c8df6deea03624c1b61
http://dspace.ucuenca.edu.ec/handle/123456789/22008
dc.language.none.fl_str_mv en_US
language_invalid_str_mv en_US
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv SPRINGER VERLAG
publisher.none.fl_str_mv SPRINGER VERLAG
dc.source.none.fl_str_mv IFMBE Proceedings
reponame:Repositorio Universidad de Cuenca
instname:Universidad de Cuenca
instacron:UCUENCA
instname_str Universidad de Cuenca
instacron_str UCUENCA
institution UCUENCA
reponame_str Repositorio Universidad de Cuenca
collection Repositorio Universidad de Cuenca
repository.name.fl_str_mv Repositorio Universidad de Cuenca - Universidad de Cuenca
repository.mail.fl_str_mv .
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