Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop

The issues of antivenom stability and distribution, and the training of health staff in the correct use of antivenoms in Latin America were discussed in a workshop held at Instituto Clodomiro Picado, Costa Rica, in September 16–19, 2008, under the auspices of the program CYTED. Participants from pub...

ver descrição completa

Detalhes bibliográficos
Autores: Gutiérrez, José María, Fan, Hui Wen, Silvera, Carmen L.M., Angulo Ugalde, Yamileth
Formato: artículo
Fecha de publicación:2009
País:Costa Rica
Recursos:Universidad de Costa Rica
Repositorio:Kérwá
OAI Identifier:oai:kerwa.ucr.ac.cr:10669/29256
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S0041010109000579
https://hdl.handle.net/10669/29256
Access Level:acceso abierto
Palavra-chave:Antivenom
Latin America
Snakebite
Envenomation
Stability
Distribution
Medical training
Snake venom
id CR_d7c5a2fbdd32ddf71949ab02fdf3dbdc
oai_identifier_str oai:kerwa.ucr.ac.cr:10669/29256
network_acronym_str CR
network_name_str Costa Rica
repository_id_str
dc.title.es_ES.fl_str_mv Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
title Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
spellingShingle Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
Gutiérrez, José María
Antivenom
Latin America
Snakebite
Envenomation
Stability
Distribution
Medical training
Snake venom
title_short Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
title_full Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
title_fullStr Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
title_full_unstemmed Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
title_sort Stability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshop
dc.creator.none.fl_str_mv Gutiérrez, José María
Fan, Hui Wen
Silvera, Carmen L.M.
Angulo Ugalde, Yamileth
author Gutiérrez, José María
author_facet Gutiérrez, José María
Fan, Hui Wen
Silvera, Carmen L.M.
Angulo Ugalde, Yamileth
author_role author
author2 Fan, Hui Wen
Silvera, Carmen L.M.
Angulo Ugalde, Yamileth
author2_role author
author
author
dc.subject.es_ES.fl_str_mv Antivenom
Latin America
Snakebite
Envenomation
Stability
Distribution
Medical training
Snake venom
topic Antivenom
Latin America
Snakebite
Envenomation
Stability
Distribution
Medical training
Snake venom
description The issues of antivenom stability and distribution, and the training of health staff in the correct use of antivenoms in Latin America were discussed in a workshop held at Instituto Clodomiro Picado, Costa Rica, in September 16–19, 2008, under the auspices of the program CYTED. Participants from public antivenom production laboratories of the region, together with representatives of the Ministries of Health, from Argentina, Paraguay, Brazil, Bolivia, Perú, Ecuador, Colombia, Venezuela, Panamá, Costa Rica and Nicaragua participated in the event. Technical advances in the study of antivenom stability and in the design of novel formulations aimed at generating products of higher stability were presented. In addition, antivenom acquisition and distribution systems in every country were presented and discussed, together with novel tools that could be useful for improving antivenom distribution, such as the software SIGEpi, developed by the Pan American Health Organization. The issue of the cold chain, as well as the most frequent causes of misuse of antivenoms in the region, were also analyzed. Finally, the experiences of training programs for health staff on the correct use of antivenoms in snakebite envenomation treatment in Latin America were presented. It was concluded that, in addition to the fostering of antivenom production and quality control, renewed efforts should be implemented at improving the stability, distribution and correct use of antivenoms in the region.
publishDate 2009
dc.date.issued.none.fl_str_mv 2009-05
dc.date.accessioned.none.fl_str_mv 2016-11-16T19:44:55Z
dc.date.available.none.fl_str_mv 2016-11-16T19:44:55Z
dc.type.none.fl_str_mv artículo original
http://purl.org/coar/resource_type/c_2df8fbb1
info:eu-repo/semantics/article
format article
dc.identifier.citation.none.fl_str_mv http://www.sciencedirect.com/science/article/pii/S0041010109000579
dc.identifier.issn.none.fl_str_mv 0041-0101
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10669/29256
dc.identifier.doi.none.fl_str_mv 10.1016/j.toxicon.2009.01.020
url http://www.sciencedirect.com/science/article/pii/S0041010109000579
https://hdl.handle.net/10669/29256
identifier_str_mv 0041-0101
10.1016/j.toxicon.2009.01.020
dc.language.iso.es_ES.fl_str_mv en_US
language_invalid_str_mv en_US
dc.rights.none.fl_str_mv acceso abierto
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
rights_invalid_str_mv acceso abierto
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.source.es_ES.fl_str_mv Toxicon; Volumen 53, Número 6. 2009
dc.source.none.fl_str_mv reponame:Kérwá
instname:Universidad de Costa Rica
instacron:UCR
instname_str Universidad de Costa Rica
instacron_str UCR
institution UCR
reponame_str Kérwá
collection Kérwá
bitstream.url.fl_str_mv https://www.kerwa.ucr.ac.cr/bitstreams/70539133-1535-4ef2-b61f-14559a11b138/download
https://www.kerwa.ucr.ac.cr/bitstreams/053ccde9-7b71-4cb8-9cc9-47bc20a5a56f/download
https://www.kerwa.ucr.ac.cr/bitstreams/b1bb4362-939c-4037-a7f7-363fa98935f9/download
https://www.kerwa.ucr.ac.cr/bitstreams/2432d1a7-590c-4c7c-b8c2-7551710f963b/download
bitstream.checksum.fl_str_mv 9407e1ebc2385c669da1b10e6ea8d5fc
f50576518b3bae75511d86d2583c3556
f390d89ef134b2cf93d74a0f1594d4ae
19bb3ae319d5a6fcf3779395b81c2dfc
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
repository.name.fl_str_mv Kérwá - Universidad de Costa Rica
repository.mail.fl_str_mv meilyn.garro@ucr.ac.cr
_version_ 1849325629213769728
spelling Gutiérrez, José María6a9bac5f-130f-4977-8ddf-ab97fcafacc4600Fan, Hui Wenec92836a-eb96-4856-b898-b2cd57bce5e4600Silvera, Carmen L.M.ff1c8c9c-e86c-47d4-ac53-c8d74c7f242eAngulo Ugalde, Yamileth76ca7ee8-9d85-4e33-9dc1-357e266c94716002016-11-16T19:44:55Z2016-11-16T19:44:55Z2009-05http://www.sciencedirect.com/science/article/pii/S00410101090005790041-0101https://hdl.handle.net/10669/2925610.1016/j.toxicon.2009.01.020The issues of antivenom stability and distribution, and the training of health staff in the correct use of antivenoms in Latin America were discussed in a workshop held at Instituto Clodomiro Picado, Costa Rica, in September 16–19, 2008, under the auspices of the program CYTED. Participants from public antivenom production laboratories of the region, together with representatives of the Ministries of Health, from Argentina, Paraguay, Brazil, Bolivia, Perú, Ecuador, Colombia, Venezuela, Panamá, Costa Rica and Nicaragua participated in the event. Technical advances in the study of antivenom stability and in the design of novel formulations aimed at generating products of higher stability were presented. In addition, antivenom acquisition and distribution systems in every country were presented and discussed, together with novel tools that could be useful for improving antivenom distribution, such as the software SIGEpi, developed by the Pan American Health Organization. The issue of the cold chain, as well as the most frequent causes of misuse of antivenoms in the region, were also analyzed. Finally, the experiences of training programs for health staff on the correct use of antivenoms in snakebite envenomation treatment in Latin America were presented. It was concluded that, in addition to the fostering of antivenom production and quality control, renewed efforts should be implemented at improving the stability, distribution and correct use of antivenoms in the region.UCR::Vicerrectoría de Investigación::Unidades de Investigación::Ciencias de la Salud::Instituto Clodomiro Picado (ICP)UCR::Vicerrectoría de Docencia::Salud::Facultad de Medicina::Escuela de Medicinaen_USacceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessToxicon; Volumen 53, Número 6. 2009reponame:Kérwáinstname:Universidad de Costa Ricainstacron:UCRAntivenomLatin AmericaSnakebiteEnvenomationStabilityDistributionMedical trainingSnake venomStability, distribution and use of antivenoms for snakebite envenomation in Latin America: Report of a workshopartículo originalhttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleTHUMBNAIL274_2009_Toxicon_Gutiérrez_workshop.pdf.jpg274_2009_Toxicon_Gutiérrez_workshop.pdf.jpgGenerated Thumbnailimage/jpeg4894https://www.kerwa.ucr.ac.cr/bitstreams/70539133-1535-4ef2-b61f-14559a11b138/download9407e1ebc2385c669da1b10e6ea8d5fcMD54ORIGINAL274_2009_Toxicon_Gutiérrez_workshop.pdf274_2009_Toxicon_Gutiérrez_workshop.pdfapplication/pdf141664https://www.kerwa.ucr.ac.cr/bitstreams/053ccde9-7b71-4cb8-9cc9-47bc20a5a56f/downloadf50576518b3bae75511d86d2583c3556MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-82437https://www.kerwa.ucr.ac.cr/bitstreams/b1bb4362-939c-4037-a7f7-363fa98935f9/downloadf390d89ef134b2cf93d74a0f1594d4aeMD52TEXT274_2009_Toxicon_Gutiérrez_workshop.pdf.txt274_2009_Toxicon_Gutiérrez_workshop.pdf.txtExtracted texttext/plain33575https://www.kerwa.ucr.ac.cr/bitstreams/2432d1a7-590c-4c7c-b8c2-7551710f963b/download19bb3ae319d5a6fcf3779395b81c2dfcMD5310669/292562021-04-12 09:28:57.52open.accessoai:kerwa.ucr.ac.cr:10669/29256https://www.kerwa.ucr.ac.crInstitucionalhttp://www.kerwa.ucr.ac.crUniversidadhttp://www.ucr.ac.crhttps://kerwa.ucr.ac.cr/oai/requestmeilyn.garro@ucr.ac.crCosta RicaNo aplicaNo aplicaNo aplicaopendoar:18712025-03-29T18:09:30.165Kérwá - Universidad de Costa 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
score 15,812429