Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis

Pyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen synthesis, whereby it could be considered a specific biomarker of bone resorption...

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Detalles Bibliográficos
Autores: González Quesada DDS, MSc, Jorge, Rivera Alvarez DDS, Sonia
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Costa Rica
Institución:Universidad de Costa Rica
Repositorio:Portal de Revistas UCR
Idioma:inglés
OAI Identifier:oai:portal.ucr.ac.cr:article/26497
Acceso en línea:https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497
Access Level:acceso abierto
Palabra clave:Pyridinoline
Periodontitis
Gingival crevicular fluid
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spelling Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic PeriodontitisGonzález Quesada DDS, MSc, JorgeRivera Alvarez DDS, SoniaPyridinolinePeriodontitisGingival crevicular fluidPyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen synthesis, whereby it could be considered a specific biomarker of bone resorption. The aim of this study is to determine the levels of ICTP in the GCF patients with progressive chronic periodontitis. In 14 inactive sites and 14 active sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples. It was determined that the levels of ICTP in the active sites were high and the difference inactive sites were statistically significant (p = 0.001). Based in our results we concluded that the high levels of ICTP suggests its use as a predictor of alveolar bone destruction.Universidad de Costa Rica2016-10-07info:eu-repo/semantics/publishedVersionArticleOriginal clinical reseachartículo originalhttp://purl.org/coar/resource_type/c_2df8fbb1info:eu-repo/semantics/articleapplication/pdftext/htmlhttps://revistas.ucr.ac.cr/index.php/Odontos/article/view/2649710.15517/ijds.v0i0.26497Odovtos - International Journal of Dental Sciences; Vol. 18 No. 3 (2016): Odovtos - International Journal of Dental Sciences V.3 (September-December)-2016; 61-68Odovtos International Journal of Dental Sciences; Vol. 18 Núm. 3 (2016): Odovtos - International Journal of Dental Sciences V.3 (September-December)-2016; 61-682215-34111659-104610.15517/ijds.v18i3reponame:Portal de Revistas UCRinstname:Universidad de Costa Ricainstacron:UCRenghttps://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497/26727https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497/27975Derechos de autor 2016 Odovtos International Journal of Dental Sciencesacceso abiertohttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccess2017-01-19T19:46:37Zoai:portal.ucr.ac.cr:article/26497Portal de revistashttps://revistas.ucr.ac.cr/Universidadhttp://www.ucr.ac.crhttps://revistas.ucr.ac.cr/index.php/index/oaijorge.polanco@ucr.ac.crCosta RicaNo aplicaNo aplicaNo aplicaopendoar:2025-08-13T10:43:52.210Portal de Revistas UCR - Universidad de Costa Ricafalse
dc.title.none.fl_str_mv Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
title Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
spellingShingle Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
González Quesada DDS, MSc, Jorge
Pyridinoline
Periodontitis
Gingival crevicular fluid
title_short Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
title_full Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
title_fullStr Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
title_full_unstemmed Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
title_sort Pyridinoline (ICTP) Levels in Gingival Crevicular Fluid (GCF) in Chronic Periodontitis
dc.creator.none.fl_str_mv González Quesada DDS, MSc, Jorge
Rivera Alvarez DDS, Sonia
author González Quesada DDS, MSc, Jorge
author_facet González Quesada DDS, MSc, Jorge
Rivera Alvarez DDS, Sonia
author_role author
author2 Rivera Alvarez DDS, Sonia
author2_role author
dc.subject.none.fl_str_mv Pyridinoline
Periodontitis
Gingival crevicular fluid
topic Pyridinoline
Periodontitis
Gingival crevicular fluid
description Pyridinoline (ICTP) is a molecule of collagen degradation that after bone resorption and degradation of the collagen matrix is released into the circulation and can not pass anabolic pathways and reused during collagen synthesis, whereby it could be considered a specific biomarker of bone resorption. The aim of this study is to determine the levels of ICTP in the GCF patients with progressive chronic periodontitis. In 14 inactive sites and 14 active sites determined by the method of tolerance, ICTP levels were measured using the ICTP EIA. Uni Q, the results were analyzed using Stata 7.0 program and the student-test for nonparametric samples. It was determined that the levels of ICTP in the active sites were high and the difference inactive sites were statistically significant (p = 0.001). Based in our results we concluded that the high levels of ICTP suggests its use as a predictor of alveolar bone destruction.
publishDate 2016
dc.date.none.fl_str_mv 2016-10-07
dc.type.none.fl_str_mv info:eu-repo/semantics/publishedVersion
Article
Original clinical reseach
artículo original
http://purl.org/coar/resource_type/c_2df8fbb1
info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497
10.15517/ijds.v0i0.26497
url https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497
identifier_str_mv 10.15517/ijds.v0i0.26497
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497/26727
https://revistas.ucr.ac.cr/index.php/Odontos/article/view/26497/27975
dc.rights.none.fl_str_mv Derechos de autor 2016 Odovtos International Journal of Dental Sciences
acceso abierto
http://purl.org/coar/access_right/c_abf2
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Derechos de autor 2016 Odovtos International Journal of Dental Sciences
acceso abierto
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
text/html
dc.publisher.none.fl_str_mv Universidad de Costa Rica
publisher.none.fl_str_mv Universidad de Costa Rica
dc.source.none.fl_str_mv Odovtos - International Journal of Dental Sciences; Vol. 18 No. 3 (2016): Odovtos - International Journal of Dental Sciences V.3 (September-December)-2016; 61-68
Odovtos International Journal of Dental Sciences; Vol. 18 Núm. 3 (2016): Odovtos - International Journal of Dental Sciences V.3 (September-December)-2016; 61-68
2215-3411
1659-1046
10.15517/ijds.v18i3
reponame:Portal de Revistas UCR
instname:Universidad de Costa Rica
instacron:UCR
instname_str Universidad de Costa Rica
instacron_str UCR
institution UCR
reponame_str Portal de Revistas UCR
collection Portal de Revistas UCR
repository.name.fl_str_mv Portal de Revistas UCR - Universidad de Costa Rica
repository.mail.fl_str_mv jorge.polanco@ucr.ac.cr
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