Polyautoimmunity in Sjögren Syndrome
Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern. The most frequent ADs observed in SS are autoimmune thyroid disease, rheumatoid art...
| Autores: | , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Colombia |
| Institución: | Universidad del Rosario |
| Repositorio: | Repositorio EdocUR - U. Rosario |
| Idioma: | inglés |
| OAI Identifier: | oai:repository.urosario.edu.co:10336/23248 |
| Acceso en línea: | https://doi.org/10.1016/j.rdc.2016.03.005 https://repository.urosario.edu.co/handle/10336/23248 |
| Access Level: | acceso abierto |
| Palabra clave: | Rituximab Antibody specificity Autoimmune disease Autoimmune hepatitis Autoimmunity Disease association Disease course Disease severity Genetic variability Human Immunopathogenesis Polyautoimmunity Priority journal Review Rheumatoid arthritis Risk assessment Risk factor Sjoegren syndrome Smoking Symptom Systemic disease Systemic lupus erythematosus Systemic sclerosis Thyroid disease Autoimmune diseases Comorbidity Genetics Immunology Sjogren's syndrome Humans Autoimmune tautology Sjögren syndrome autoimmune rheumatoid systemic Arthritis Lupus erythematosus Thyroiditis |
| Sumario: | Polyautoimmunity is defined as the presence of more than one well-defined autoimmune disease (AD) in a single patient. Polyautoimmunity is a frequent condition in Sjögren syndrome (SS) and follows a grouping pattern. The most frequent ADs observed in SS are autoimmune thyroid disease, rheumatoid arthritis, and systemic lupus erythematosus. Main factors associated with polyautoimmunity in SS are tobacco smoking and some genetic variants. The study of polyautoimmunity provides important clues for elucidating the common mechanisms of autoimmne diseases (ie, the autoimmune tautology). © 2016 Elsevier Inc. |
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