Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice

Introduction: Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) is a part of popular therapy for treating a wide range of health problems that affect metabolism and the digestive, respiratory, musculoskeletal, cardiovascular and genitourinary systems. Our aim is to provide data that co...

Descripción completa

Detalles Bibliográficos
Autores: Tevez, Mauricio Roberto, Wendel, Graciela Haydée
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2016
País:Colombia
Institución:Universidad Cooperativa de Colombia
Repositorio:Repositorio UCC
Idioma:español
OAI Identifier:oai:repository.ucc.edu.co:20.500.12494/9889
Acceso en línea:https://revistas.ucc.edu.co/index.php/sp/article/view/2519
https://hdl.handle.net/20.500.12494/9889
Access Level:acceso abierto
id CO_f2fc63d457fef6ea1a28b2a36d2f8d8b
oai_identifier_str oai:repository.ucc.edu.co:20.500.12494/9889
network_acronym_str CO
network_name_str Colombia
repository_id_str
spelling Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In MiceActividad de los extractos acuosos liofilizados de hojas y corteza de Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) sobre el tránsito intestinal en ratonesAtividade dos extratos aquosos liofilizados de folhas e casca de Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) sobre o trânsito intestinal em ratosTevez, Mauricio RobertoWendel, Graciela HaydéeIntroduction: Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) is a part of popular therapy for treating a wide range of health problems that affect metabolism and the digestive, respiratory, musculoskeletal, cardiovascular and genitourinary systems. Our aim is to provide data that contribute to validating its use as an antidiarrheal. Materials and methods: According to the literature, we used the aqueous extract of bark, the aqueous extract of leaves and a combination of both to test the resulting effects on the intestinal activity of Rockland mice. Results: The administration of leaf and bark extracts separately did not yield significant values; however, co-administration of both extracts at doses of 125, 250 and 500 mg/kg resulted in a significant decrease—and in a dose-dependent manner—of intestinal transit in Rockland mice (p <0.05; p <0.01 and p <0.01, respectively), compared to the negative control group. Conclusions: The results obtained show us that the joint use of aqueous extract of J. Rhombifolia leaves and bark has a reducing effect on normal intestinal transit in the in vivo model and supports its use in Argentine popular medicine.  Introducción: Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) es utilizada en la terapéutica popular para el tratamiento de una gran diversidad de problemas de salud que afectan al metabolismo y al sistema digestivo, respiratorio, músculo-esquelético, cardiovascular y genitourinario. Nuestro objetivo esaportar datos que permitan contribuir a la validación de su uso como antidiarreico. Metodología: conforme a referencias bibliográficas, utilizamos el extracto acuoso de la corteza, el extracto acuoso de las hojas y el empleo conjunto de ambos extractos para ensayar los efectos resultantes sobre la actividad intestinal de ratones Rockland. Resultados: la administración de los extractos de hojas y de corteza por separado no arrojaron valores significativos; sin embargo, la administración conjunta de ambos extractos a las dosis de 125, 250 y 500 mg/kg resultaron en una disminución significativa —y de manera dependiente de la dosis— del tránsito intestinal en ratones Rockland p<0,05; p<0,01 y p<0,01, respectivamente, en comparación con el grupo de control negativo. Conclusiones: los resultados obtenidos nos demuestran que la utilización conjunta del extracto acuoso de las hojas y de la corteza de J. rhombifolia poseen un significante efecto reductor del tránsito intestinal normal en el modelo invivo utilizado y que avala la utilización en la medicina popular argentina.Universidad Cooperativa de Colombia2016-10-272019-05-14T21:13:22Z2019-05-14T21:13:22ZArtículohttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://revistas.ucc.edu.co/index.php/sp/article/view/251910.16925/2382-4247.2016.02.01https://hdl.handle.net/20.500.12494/9889Spei Domus; Vol. 12 Núm. 25 (2016)Spei Domus; Vol 12 No 25 (2016)Spei Domus; v. 12 n. 25 (2016)2382-42471794-7928reponame:Repositorio UCCinstname:Universidad Cooperativa de Colombiainstacron:Universidad Cooperativa de Colombiaspahttps://revistas.ucc.edu.co/index.php/sp/article/view/2519/2620info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf22024-07-16T18:33:51Z
dc.title.none.fl_str_mv Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
Actividad de los extractos acuosos liofilizados de hojas y corteza de Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) sobre el tránsito intestinal en ratones
Atividade dos extratos aquosos liofilizados de folhas e casca de Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) sobre o trânsito intestinal em ratos
title Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
spellingShingle Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
Tevez, Mauricio Roberto
title_short Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
title_full Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
title_fullStr Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
title_full_unstemmed Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
title_sort Activity of Lyophilized Aqueous Extracts of Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) Leaves and Bark on Intestinal Transit In Mice
dc.creator.none.fl_str_mv Tevez, Mauricio Roberto
Wendel, Graciela Haydée
author Tevez, Mauricio Roberto
author_facet Tevez, Mauricio Roberto
Wendel, Graciela Haydée
author_role author
author2 Wendel, Graciela Haydée
author2_role author
description Introduction: Jodina rhombifolia (Hook. & Arn.) Reissek (Santalaceae) is a part of popular therapy for treating a wide range of health problems that affect metabolism and the digestive, respiratory, musculoskeletal, cardiovascular and genitourinary systems. Our aim is to provide data that contribute to validating its use as an antidiarrheal. Materials and methods: According to the literature, we used the aqueous extract of bark, the aqueous extract of leaves and a combination of both to test the resulting effects on the intestinal activity of Rockland mice. Results: The administration of leaf and bark extracts separately did not yield significant values; however, co-administration of both extracts at doses of 125, 250 and 500 mg/kg resulted in a significant decrease—and in a dose-dependent manner—of intestinal transit in Rockland mice (p <0.05; p <0.01 and p <0.01, respectively), compared to the negative control group. Conclusions: The results obtained show us that the joint use of aqueous extract of J. Rhombifolia leaves and bark has a reducing effect on normal intestinal transit in the in vivo model and supports its use in Argentine popular medicine.  
publishDate 2016
dc.date.none.fl_str_mv 2016-10-27
2019-05-14T21:13:22Z
2019-05-14T21:13:22Z
dc.type.none.fl_str_mv Artículo
http://purl.org/coar/resource_type/c_6501
http://purl.org/coar/version/c_970fb48d4fbd8a85
info:eu-repo/semantics/article
http://purl.org/redcol/resource_type/ART
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://revistas.ucc.edu.co/index.php/sp/article/view/2519
10.16925/2382-4247.2016.02.01
https://hdl.handle.net/20.500.12494/9889
url https://revistas.ucc.edu.co/index.php/sp/article/view/2519
https://hdl.handle.net/20.500.12494/9889
identifier_str_mv 10.16925/2382-4247.2016.02.01
dc.language.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.ucc.edu.co/index.php/sp/article/view/2519/2620
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidad Cooperativa de Colombia
publisher.none.fl_str_mv Universidad Cooperativa de Colombia
dc.source.none.fl_str_mv Spei Domus; Vol. 12 Núm. 25 (2016)
Spei Domus; Vol 12 No 25 (2016)
Spei Domus; v. 12 n. 25 (2016)
2382-4247
1794-7928
reponame:Repositorio UCC
instname:Universidad Cooperativa de Colombia
instacron:Universidad Cooperativa de Colombia
instname_str Universidad Cooperativa de Colombia
instacron_str Universidad Cooperativa de Colombia
institution Universidad Cooperativa de Colombia
reponame_str Repositorio UCC
collection Repositorio UCC
_version_ 1825053315597074432
score 15.812429

Similares en LA Referencia