Understanding the venous–arterial CO2 to arterial–venous O2 content difference ratio
Introduction Early identification of tissue hypoperfusion is a cornerstone of shock management [1]. Normal macrohemodynamic and oxygen-derived parameters do not, however, rule out the presence of tissue hypoxia [2]. In this setting, carbon dioxide (CO2)-derived variables may provide information on m...
| Autores: | , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2016 |
| País: | Colombia |
| Institución: | Universidad ICESI |
| Repositorio: | Repositorio ICESI |
| Idioma: | inglés |
| OAI Identifier: | oai:repository.icesi.edu.co:10906/82294 |
| Acceso en línea: | http://link.springer.com/10.1007/s00134-016-4233-7 http://hdl.handle.net/10906/82294 http://dx.doi.org/10.1007/s00134-016-4233-7 |
| Access Level: | acceso abierto |
| Palabra clave: | Dióxido de Carbono Microcirculación Ciencias socio biomédicas Reanimación Biomedical sciences |
| Sumario: | Introduction Early identification of tissue hypoperfusion is a cornerstone of shock management [1]. Normal macrohemodynamic and oxygen-derived parameters do not, however, rule out the presence of tissue hypoxia [2]. In this setting, carbon dioxide (CO2)-derived variables may provide information on macroand microvascular blood flow [3] and also on the presence of anaerobic metabolism [4, 5]. Importantly, variations in CO2 occur more rapidly than changes in lactate kinetics, making the former an attractive biomarker for monitoring, especially during the early stages of resuscitation [6, 7]. |
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