In Vitro and In Vivo Cytotoxicities and Antileishmanial Activities of Thymol and Hemisynthetic Derivatives

ABSTRACT: The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be consider...

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Detalles Bibliográficos
Autores: Robledo Restrepo, Sara María, Osorio Durango, Edison Javier, Muñoz Herrera, Diana Lorena, Jaramillo Pérez, Luz Marina, Restrepo Agudelo, Adriana María, Arango Acosta, Gabriel Jaime, Vélez Bernal, Iván Darío
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2005
País:Colombia
Institución:Universidad de Antioquia
Repositorio:Repositorio UdeA
Idioma:inglés
OAI Identifier:oai:bibliotecadigital.udea.edu.co:10495/24198
Acceso en línea:http://hdl.handle.net/10495/24198
Access Level:acceso abierto
Palabra clave:Timol
Thymol
Citotoxicidad
Cytotoxicity
http://aims.fao.org/aos/agrovoc/c_34251
Descripción
Sumario:ABSTRACT: The in vitro and in vivo antileishmanial and cytotoxic activities of thymol and structural derivatives in comparison to those of Glucantime were studied. The results showed here suggest that thymol and hemisynthetic derivatives have promising antileishmanial potential and could be considered as new lead structures in the search for novel antileishmanial drugs.

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