Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance

Background: Exercise training improves performance and biochemical parameters on average, but wide interindividual variability exists, with individuals classified as responders (R) or non-responders (NRs), especially between populations with higher or lower levels of insulin resistance. This study a...

Descripción completa

Detalles Bibliográficos
Autores: Álvarez, Cristian, Ramírez-Campillo, Rodrigo, Izquierdo, Mikel, Ramírez-Vélez, Robinson
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:Colombia
Institución:Universidad del Rosario
Repositorio:Repositorio EdocUR - U. Rosario
Idioma:inglés
OAI Identifier:oai:repository.urosario.edu.co:10336/21757
Acceso en línea:https://doi.org/10.3389/fphys.2017.00479
https://repository.urosario.edu.co/handle/10336/21757
Access Level:acceso abierto
Palabra clave:Enfermedades
Glucose
Insulin
Adult
Anthropometry
Article
Body mass
Cardiovascular function
Controlled study
Diet restriction
Female
Glucose blood level
Glycemic control
High intensity interval training
id CO_ccffb31ec8b41daee44de2a0ab0ca7f7
oai_identifier_str oai:repository.urosario.edu.co:10336/21757
network_acronym_str CO
network_name_str Colombia
repository_id_str
spelling Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistanceÁlvarez, CristianRamírez-Campillo, RodrigoIzquierdo, MikelRamírez-Vélez, RobinsonEnfermedadesGlucoseInsulinAdultAnthropometryArticleBody massCardiovascular functionControlled studyDiet restrictionFemaleGlucose blood levelGlycemic controlHigh intensity interval trainingBackground: Exercise training improves performance and biochemical parameters on average, but wide interindividual variability exists, with individuals classified as responders (R) or non-responders (NRs), especially between populations with higher or lower levels of insulin resistance. This study assessed the effects of high-intensity interval training (HIIT) and the prevalence of NRs in adult women with higher and lower levels of insulin resistance. Methods: Forty adult women were assigned to a HIIT program, and after training were analyzed in two groups; a group with higher insulin resistance (H-IR, 40 ± 6 years; BMI: 29.5 ± 3.7 kg/m2; n = 20) and a group with lower insulin resistance (L-IR, 35 ± 9 years; 27.8 ± 2.8 kg/m2; n = 20). Anthropometric, cardiovascular, metabolic, and performance variables were measured at baseline and after 10 weeks of training. Results: There were significant training-induced changes [delta percent (Δ%)] in fasting glucose, fasting insulin, and homeostasis model assessment of insulin resistance (HOMA-IR) scores in the H-IR group (-8.8, -26.5, -32.1%, p < 0.0001), whereas no significant changes were observed in the L-IR. Both groups showed significant pre-post changes in other anthropometric variables [waist circumference (-5.2, p < 0.010, and -3.8%, p = 0.046) and tricipital (-13.3, p < 0.010, and -13.6%, p < 0.0001), supra-iliac (-19.4, p < 0.0001, and -13.6%, p < 0.0001), and abdominal (-18.2, p < 0.0001, and -15.6%, p < 0.010) skinfold measurements]. Systolic blood pressure decreased significantly only in the L-IR group (-3.2%, p < 0.010). Both groups showed significant increases in 1RMLE (+12.9, p < 0.010, and +14.7%, p = 0.045). There were significant differences in the prevalence of NRs between the H-IR and L-IR groups for fasting glucose (25 vs. 95%, p < 0.0001) and fasting insulin (p = 0.025) but not for HOMA-IR (25 vs. 45%, p = 0.185). Conclusion: Independent of the "magnitude" of the cardiometabolic disease (i.e., higher vs. lower insulin resistance), no differences were observed in the NRs prevalence with regard to improved HOMA-IR or to anthropometric, cardiovascular, and muscle performance co-variables after 10 weeks of HIIT in sedentary adult women. This research demonstrates the protective effect of HIIT against cardiometabolic disease progression in a sedentary population. © 2017 álvarez, Ramírez-Campillo, Ramírez-Vélez and Izquierdo.20172020-04-23T22:57:11Zinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.3389/fphys.2017.004791664-042Xhttps://repository.urosario.edu.co/handle/10336/21757reponame:Repositorio EdocUR - U. Rosarioinstname:Universidad del Rosarioinstacron:Universidad del Rosarioenghttps://www.frontiersin.org/articles/10.3389/fphys.2017.00479/fullinfo:eu-repo/semantics/openAccess2020-05-13T14:47:40Z
dc.title.none.fl_str_mv Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
title Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
spellingShingle Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
Álvarez, Cristian
Enfermedades
Glucose
Insulin
Adult
Anthropometry
Article
Body mass
Cardiovascular function
Controlled study
Diet restriction
Female
Glucose blood level
Glycemic control
High intensity interval training
title_short Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
title_full Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
title_fullStr Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
title_full_unstemmed Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
title_sort Prevalence of non-responders for glucose control markers after 10 weeks of high-intensity interval training in adult women with higher and lower insulin resistance
dc.creator.none.fl_str_mv Álvarez, Cristian
Ramírez-Campillo, Rodrigo
Izquierdo, Mikel
Ramírez-Vélez, Robinson
author Álvarez, Cristian
author_facet Álvarez, Cristian
Ramírez-Campillo, Rodrigo
Izquierdo, Mikel
Ramírez-Vélez, Robinson
author_role author
author2 Ramírez-Campillo, Rodrigo
Izquierdo, Mikel
Ramírez-Vélez, Robinson
author2_role author
author
author
dc.subject.none.fl_str_mv Enfermedades
Glucose
Insulin
Adult
Anthropometry
Article
Body mass
Cardiovascular function
Controlled study
Diet restriction
Female
Glucose blood level
Glycemic control
High intensity interval training
topic Enfermedades
Glucose
Insulin
Adult
Anthropometry
Article
Body mass
Cardiovascular function
Controlled study
Diet restriction
Female
Glucose blood level
Glycemic control
High intensity interval training
description Background: Exercise training improves performance and biochemical parameters on average, but wide interindividual variability exists, with individuals classified as responders (R) or non-responders (NRs), especially between populations with higher or lower levels of insulin resistance. This study assessed the effects of high-intensity interval training (HIIT) and the prevalence of NRs in adult women with higher and lower levels of insulin resistance. Methods: Forty adult women were assigned to a HIIT program, and after training were analyzed in two groups; a group with higher insulin resistance (H-IR, 40 ± 6 years; BMI: 29.5 ± 3.7 kg/m2; n = 20) and a group with lower insulin resistance (L-IR, 35 ± 9 years; 27.8 ± 2.8 kg/m2; n = 20). Anthropometric, cardiovascular, metabolic, and performance variables were measured at baseline and after 10 weeks of training. Results: There were significant training-induced changes [delta percent (Δ%)] in fasting glucose, fasting insulin, and homeostasis model assessment of insulin resistance (HOMA-IR) scores in the H-IR group (-8.8, -26.5, -32.1%, p < 0.0001), whereas no significant changes were observed in the L-IR. Both groups showed significant pre-post changes in other anthropometric variables [waist circumference (-5.2, p < 0.010, and -3.8%, p = 0.046) and tricipital (-13.3, p < 0.010, and -13.6%, p < 0.0001), supra-iliac (-19.4, p < 0.0001, and -13.6%, p < 0.0001), and abdominal (-18.2, p < 0.0001, and -15.6%, p < 0.010) skinfold measurements]. Systolic blood pressure decreased significantly only in the L-IR group (-3.2%, p < 0.010). Both groups showed significant increases in 1RMLE (+12.9, p < 0.010, and +14.7%, p = 0.045). There were significant differences in the prevalence of NRs between the H-IR and L-IR groups for fasting glucose (25 vs. 95%, p < 0.0001) and fasting insulin (p = 0.025) but not for HOMA-IR (25 vs. 45%, p = 0.185). Conclusion: Independent of the "magnitude" of the cardiometabolic disease (i.e., higher vs. lower insulin resistance), no differences were observed in the NRs prevalence with regard to improved HOMA-IR or to anthropometric, cardiovascular, and muscle performance co-variables after 10 weeks of HIIT in sedentary adult women. This research demonstrates the protective effect of HIIT against cardiometabolic disease progression in a sedentary population. © 2017 álvarez, Ramírez-Campillo, Ramírez-Vélez and Izquierdo.
publishDate 2017
dc.date.none.fl_str_mv 2017
2020-04-23T22:57:11Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.3389/fphys.2017.00479
1664-042X
https://repository.urosario.edu.co/handle/10336/21757
url https://doi.org/10.3389/fphys.2017.00479
https://repository.urosario.edu.co/handle/10336/21757
identifier_str_mv 1664-042X
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://www.frontiersin.org/articles/10.3389/fphys.2017.00479/full
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositorio EdocUR - U. Rosario
instname:Universidad del Rosario
instacron:Universidad del Rosario
instname_str Universidad del Rosario
instacron_str Universidad del Rosario
institution Universidad del Rosario
reponame_str Repositorio EdocUR - U. Rosario
collection Repositorio EdocUR - U. Rosario
_version_ 1825051674981433344
score 15,812429

Similares en LA Referencia