Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians

4 páginas

Detalles Bibliográficos
Autores: Vargas M., Bustamante C., Villarraga E.
Tipo de recurso: artículo
Fecha de publicación:2015
País:Colombia
Institución:Universidad de la Sabana
Repositorio:Repositorio Universidad de la Sabana
Idioma:inglés
OAI Identifier:oai:intellectum.unisabana.edu.co:10818/36914
Acceso en línea:https://www.longdom.org/open-access/bioequivalence-study-of-two-formulations-containing-rosuvastatin-40mg-tablets-in-healthy-colombians-jbb-1000245.pdf
http://hdl.handle.net/10818/36914
Access Level:acceso abierto
Palabra clave:Bioequivalence
Rosuvastatin
Cholesterol
Statin
Pharmacokinetic
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spelling Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy ColombiansVargas M.Bustamante C.Villarraga E.BioequivalenceRosuvastatinCholesterolStatinPharmacokinetic4 páginasThis is a pharmacokinetic study of two formulations containing Rosuvastatin 40 mg, with the aim to compare the Bioavailability between the Test product (Rosuvastatin made by Laboratorios Tecnoquímicas S.A., Colombia) and the Reference product (Crestor® made by Laboratorios AstraZeneca) in order to declare the Bioequivalence between both formulations. For this, an open-label, two period and two sequences previously randomized, crossover study in 30 healthy volunteers was developed, with a single 40 mg dose in fasting conditions, a washout period of 7 days and 14 plasma samples collection between 0 and 48 hours. For the identification and assessment of plasma Rosuvastatin, an ultra-high performance liquid chromatography coupled to tandem mass spectrometer, UHPLC MS/ MS was the analytical method performed.Journal of J Bioequivalence & Bioavailability8/28/2019 14:222019-08-28T19:22:42Z2015articlepublishedVersioninfo:eu-repo/semantics/articleapplication/pdf0975-0851https://www.longdom.org/open-access/bioequivalence-study-of-two-formulations-containing-rosuvastatin-40mg-tablets-in-healthy-colombians-jbb-1000245.pdfhttp://hdl.handle.net/10818/3691410.4172/jbb.1000245Universidad de La SabanaIntellectum Repositorio Universidad de La Sabanareponame:Repositorio Universidad de la Sabanainstname:Universidad de la Sabanainstacron:Universidad de la SabanaengJ Bioequiv Availab 2015, 7:5Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccess2022-05-10T10:18:34Z
dc.title.none.fl_str_mv Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
title Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
spellingShingle Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
Vargas M.
Bioequivalence
Rosuvastatin
Cholesterol
Statin
Pharmacokinetic
title_short Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
title_full Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
title_fullStr Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
title_full_unstemmed Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
title_sort Bioequivalence Study of Two Formulations Containing Rosuvastatin 40 Mg Tablets in Healthy Colombians
dc.creator.none.fl_str_mv Vargas M.
Bustamante C.
Villarraga E.
author Vargas M.
author_facet Vargas M.
Bustamante C.
Villarraga E.
author_role author
author2 Bustamante C.
Villarraga E.
author2_role author
author
dc.subject.none.fl_str_mv Bioequivalence
Rosuvastatin
Cholesterol
Statin
Pharmacokinetic
topic Bioequivalence
Rosuvastatin
Cholesterol
Statin
Pharmacokinetic
description 4 páginas
publishDate 2015
dc.date.none.fl_str_mv 2015
2019-08-28T19:22:42Z
8/28/2019 14:22
dc.type.none.fl_str_mv article
publishedVersion
info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv 0975-0851
https://www.longdom.org/open-access/bioequivalence-study-of-two-formulations-containing-rosuvastatin-40mg-tablets-in-healthy-colombians-jbb-1000245.pdf
http://hdl.handle.net/10818/36914
10.4172/jbb.1000245
identifier_str_mv 0975-0851
10.4172/jbb.1000245
url https://www.longdom.org/open-access/bioequivalence-study-of-two-formulations-containing-rosuvastatin-40mg-tablets-in-healthy-colombians-jbb-1000245.pdf
http://hdl.handle.net/10818/36914
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv J Bioequiv Availab 2015, 7:5
dc.rights.none.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Journal of J Bioequivalence & Bioavailability
publisher.none.fl_str_mv Journal of J Bioequivalence & Bioavailability
dc.source.none.fl_str_mv Universidad de La Sabana
Intellectum Repositorio Universidad de La Sabana
reponame:Repositorio Universidad de la Sabana
instname:Universidad de la Sabana
instacron:Universidad de la Sabana
instname_str Universidad de la Sabana
instacron_str Universidad de la Sabana
institution Universidad de la Sabana
reponame_str Repositorio Universidad de la Sabana
collection Repositorio Universidad de la Sabana
_version_ 1825050787649159168
score 15.81155

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