Multicenter evaluation of ceftolozane/tazobactam for serious infections caused by carbapenem-resistant pseudomonas aeruginosa

A multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in...

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Detalles Bibliográficos
Autores: Munita, Jose M., Aitken, Samuel L., Miller, William R., Perez, Federico, Rosa, Rossana, Shimose, Luis A., Lichtenberger, Paola N., Abbo, Lilian M., Jain, Rupali, Nigo, Masayuki, Wanger, Audrey, Araos, Rafael, Tran, Truc T., Adachi, Javier, Rakita, Robert, Shelburne, Samuel, Bonomo, Robert A., Arias, Cesar A.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2020
País:Colombia
Institución:Universidad El Bosque
Repositorio:Repositorio U. El Bosque
Idioma:inglés
OAI Identifier:oai:repositorio.unbosque.edu.co:20.500.12495/3679
Acceso en línea:http://hdl.handle.net/20.500.12495/3679
https://doi.org/10.1093/cid/cix014
https://repositorio.unbosque.edu.co
Access Level:acceso abierto
Palabra clave:Ceftolozane
Carbapenem resistant
P. aeruginosa
Multidrug resistant
Descripción
Sumario:A multicenter, retrospective study of patients infected with carbapenem-resistant Pseudomonas aeruginosa who were treated with ceftolozane/tazobactam was performed. Among 35 patients, pneumonia was the most common indication and treatment was successful in 26 (74%). Treatment failure was observed in all cases where isolates demonstrated ceftolozane-tazobactam minimum inhibitory concentrations ≥8 μg/mL.

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