Anormalidad de Pseudo Chediak-Higashi en un caso de Leucemia Mieloide Aguda, observado en sangre periférica
ABSTRACT: Pseudo Chediak Higschi granules have been reported in myeloid neoplasms, especially in acute myeloid leukemias with maturation and with translocation t(8;21)(q22;q22) (RUNX1T1). These granules are different to Auer bodies and they correspond to fine, larger and irregular intra-cytoplasmic...
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| Format: | article |
| Status: | Published version |
| Publication Date: | 2013 |
| Country: | Colombia |
| Institution: | Universidad de Antioquia |
| Repository: | Repositorio UdeA |
| Language: | Spanish |
| OAI Identifier: | oai:bibliotecadigital.udea.edu.co:10495/10446 |
| Online Access: | http://hdl.handle.net/10495/10446 |
| Access Level: | Open access |
| Keyword: | Extendido de sangre periférica Leucemia mieloide Síndrome de Chediak-Higashi Translocación bacteriana Translocación de cromosomas Bacterial translocation Chediak-Higashi Syndrome Myeloid Leukemia |
| Summary: | ABSTRACT: Pseudo Chediak Higschi granules have been reported in myeloid neoplasms, especially in acute myeloid leukemias with maturation and with translocation t(8;21)(q22;q22) (RUNX1T1). These granules are different to Auer bodies and they correspond to fine, larger and irregular intra-cytoplasmic structures. Herein, hematological findings of a patient with diagnosis of acute myeloid leukemia are presented, in accordance with World Health Organization criteria. In the peripheral blood smear, unique or multiple Pseudo Chediak Higashi granules with a pink color and crystalloid aspect were observed, especially in blast cells and neutrophilic myelocites. |
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