Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas

ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpi...

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Detalles Bibliográficos
Autores: Gómez Betancur, Isabel Cristina, Benjumea Gutiérrez, Dora María, Mejía, Natalia, León, Juan F., Gómez, Juan E.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2019
País:Colombia
Institución:Universidad de Antioquia
Repositorio:Repositorio UdeA
Idioma:inglés
OAI Identifier:oai:bibliotecadigital.udea.edu.co:10495/20250
Acceso en línea:http://hdl.handle.net/10495/20250
Access Level:acceso abierto
Palabra clave:Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
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spelling Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) MaasGómez Betancur, Isabel CristinaBenjumea Gutiérrez, Dora MaríaMejía, NataliaLeón, Juan F.Gómez, Juan E.Aceites esencialesEssential oilsExtractos de hojaLeaf extractsMicropropagaciónMicropropagationRenealmia alpiniaAntinociceptivehttp://aims.fao.org/aos/agrovoc/c_2669http://aims.fao.org/aos/agrovoc/c_35308http://aims.fao.org/aos/agrovoc/c_24136ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics.COL0014476Acg Publishing Press ReleaseToxinología Alternativas Terapéuticas y AlimentariasTurquía2021-06-22T22:34:27Z2021-06-22T22:34:27Z2019info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/resource_type/c_2df8fbb1https://purl.org/redcol/resource_type/ARTArtículo de investigación8application/pdfapplication/pdfhttp://hdl.handle.net/10495/2025010.25135/rnp.70.18.01.0841307-6167engRec. Nat. Prod.info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by-nc-nd/2.5/co/http://purl.org/coar/access_right/c_abf2https://creativecommons.org/licenses/by-nc-nd/4.0/reponame:Repositorio UdeAinstname:Universidad de Antioquiainstacron:Universidad de Antioquia2021-06-22T22:34:27Z
dc.title.none.fl_str_mv Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
spellingShingle Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
Gómez Betancur, Isabel Cristina
Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
title_short Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_full Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_fullStr Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_full_unstemmed Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
title_sort Antinociceptive Activity of Essential Oils from Wild Growing and Micropropagated Plants of Renealmia alpinia (Rottb.) Maas
dc.creator.none.fl_str_mv Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
author Gómez Betancur, Isabel Cristina
author_facet Gómez Betancur, Isabel Cristina
Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
author_role author
author2 Benjumea Gutiérrez, Dora María
Mejía, Natalia
León, Juan F.
Gómez, Juan E.
author2_role author
author
author
author
dc.subject.none.fl_str_mv Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
topic Aceites esenciales
Essential oils
Extractos de hoja
Leaf extracts
Micropropagación
Micropropagation
Renealmia alpinia
Antinociceptive
http://aims.fao.org/aos/agrovoc/c_2669
http://aims.fao.org/aos/agrovoc/c_35308
http://aims.fao.org/aos/agrovoc/c_24136
description ABSTRACT: Renealmia alpinia is a medicinal plant that has been cultivated and used for the treatment of headaches, abdominal pain, as a febrifuge and to treat snake bites in southeast Colombia and in the Caribbean islands. Moreover, its edible fruits are commonly used as spice in Mexico. The R. alpinia leave-extracts have shown enzymatic inhibition of Bothrops atrox and Bothrops asper snake poison. The extracts also showed effects as a peripheral analgesic agent. This report investigates the analgesic activity of the essential oils obtained by hydrodistillation from wild and in vitro propagation samples of R. alpinia as well as the chemical profile using GC-MS. The essential oils isolated from R. alpinia evaluated on concentrations of 50, 75 and 100 mg/kg showed significant antinociceptive effects in the test of acetic-acid-induced abdominal writhing, compared to the control animals. The essential oil of the wild flora leaves showed the highest percentage of pain inhibition by 200 mg/kg, concluding that the essential oil of R. alpinia presents antinociceptive activity in an in vivo model. These results help us to understand the traditional use of R. alpinia to treat pain and make it a potential source for the development of phytopharmaceutics.
publishDate 2019
dc.date.none.fl_str_mv 2019
2021-06-22T22:34:27Z
2021-06-22T22:34:27Z
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
http://purl.org/coar/resource_type/c_2df8fbb1
https://purl.org/redcol/resource_type/ART
Artículo de investigación
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10495/20250
10.25135/rnp.70.18.01.084
1307-6167
url http://hdl.handle.net/10495/20250
identifier_str_mv 10.25135/rnp.70.18.01.084
1307-6167
dc.language.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Rec. Nat. Prod.
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by-nc-nd/2.5/co/
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by-nc-nd/2.5/co/
http://purl.org/coar/access_right/c_abf2
https://creativecommons.org/licenses/by-nc-nd/4.0/
dc.format.none.fl_str_mv 8
application/pdf
application/pdf
dc.publisher.none.fl_str_mv Acg Publishing Press Release
Toxinología Alternativas Terapéuticas y Alimentarias
Turquía
publisher.none.fl_str_mv Acg Publishing Press Release
Toxinología Alternativas Terapéuticas y Alimentarias
Turquía
dc.source.none.fl_str_mv reponame:Repositorio UdeA
instname:Universidad de Antioquia
instacron:Universidad de Antioquia
instname_str Universidad de Antioquia
instacron_str Universidad de Antioquia
institution Universidad de Antioquia
reponame_str Repositorio UdeA
collection Repositorio UdeA
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score 15,812429

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