HLA genes in Barranquilla (North Colombia): Searching for cryptic Amerindian genes

America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and...

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Bibliographic Details
Authors: Arnaiz-Villena A., Bayona B., Palacio-Gruber J., Hernandez Aguirre, Enio, Muñiz E., Campos C., Juarez I., Gomez-Casado E., Martín-Villa J.M., Silvera C.
Format: article
Status:Published version
Publication Date:2023
Country:Colombia
Institution:Universidad Cooperativa de Colombia
Repository:Repositorio UCC
OAI Identifier:oai:repository.ucc.edu.co:20.500.12494/49633
Online Access:https://doi.org/10.1016/j.humimm.2017.11.003
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85034270363&doi=10.1016%2fj.humimm.2017.11.003&partnerID=40&md5=7158c0974f243f91d22a64f1c399925f
https://hdl.handle.net/20.500.12494/49633
Access Level:Open access
Keyword:AFRICAN
AMERINDIAN
BARRANQUILLA
CAUCASOID
COLOMBIA
CUBA
HLA
Description
Summary:America First Inhabitants population (Amerindians, Na Dene and Eskimos) underwent a drastic population reduction and gene exchange after Europeans and Africans arrival after 1492 AD. Barranquilla population may be a good model to study present day population admixture in South America. HLA-A, -B and -DRB1 DNA typing has been performed in 188 unrelated individuals originated in the area and speak Spanish language; they showed apparent European/African and mixed characters. HLA genetic European/African features were found and only 1.85% Amerindian one. This contrasts with neighboring Cuban population where 10% HLA Amerindian characters appear. © 2017.