An antibody profile of systemic lupus erythematosus detected by antigen microarray
Patients with systemic lupus erythematosus (SLE) produce antibodies to many different self-antigens. Here, we investigated antibodies in SLE sera using an antigen microarray containing many hundreds of antigens, mostly self-antigens. The aim was to detect sets of antibody reactivities characteristic...
| Autores: | , , , , , , , , , , , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2010 |
| País: | Colombia |
| Institución: | Universidad del Rosario |
| Repositorio: | Repositorio EdocUR - U. Rosario |
| Idioma: | inglés |
| OAI Identifier: | oai:repository.urosario.edu.co:10336/26025 |
| Acceso en línea: | https://doi.org/10.1111/j.1365-2567.2010.03245.x https://repository.urosario.edu.co/handle/10336/26025 |
| Access Level: | acceso abierto |
| Palabra clave: | 12E7 Antigen Adult Antibodies Anticardiolipin Antinuclear Antigens CD Autoantibodies Cell Adhesion Molecules Collagen Type III Down-Regulation Female Herpesvirus 4 Human Humans Hyaluronic Acid Immunoglobulin G Immunoglobulin M Insulin-Like Growth Factor Binding Protein 1 Lupus Erythematosus Systemic Lupus Nephritis Male Middle Aged Peroxidase Protein Array Analysis Sensitivity and Specificity Up-Regulation |
| Sumario: | Patients with systemic lupus erythematosus (SLE) produce antibodies to many different self-antigens. Here, we investigated antibodies in SLE sera using an antigen microarray containing many hundreds of antigens, mostly self-antigens. The aim was to detect sets of antibody reactivities characteristic of SLE patients in each of various clinical states – SLE patients with acute lupus nephritis, SLE patients in renal remission, and SLE patients who had never had renal involvement |
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