Dissecting the functional roles of the conserved nxxe and hxe motifs of the adp-dependent glucokinase from thermococcus litoralis
The activity of the ADP-dependent glucokinase from Thermococcus litoralis (TIGK) relies on the highly conserved motifs NXXE (i.e. Asn-Xaa-Xaa-Glu) and HXE (i.e. His-Xaa-Glu). Site-directed mutagenesis of residues Glu279 (11XE) and Glu308 (NXXE) leads to e
| Autores: | , , , |
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| Tipo de documento: | artigo |
| Estado: | Versão publicada |
| Data de publicação: | 2015 |
| País: | Chile |
| Idioma: | inglês |
| OAI Identifier: | oai:repositorio.anid.cl:10533/232059 |
| Acesso em linha: | https://hdl.handle.net/10533/232059 |
| Access Level: | Acceso aberto |
| Resumo: | The activity of the ADP-dependent glucokinase from Thermococcus litoralis (TIGK) relies on the highly conserved motifs NXXE (i.e. Asn-Xaa-Xaa-Glu) and HXE (i.e. His-Xaa-Glu). Site-directed mutagenesis of residues Glu279 (11XE) and Glu308 (NXXE) leads to e |
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