Unfolded protein response transcription factor XBP-1 does not influence prion replication or pathogenesis

The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of the UPR that activates genes involv

Detalles Bibliográficos
Autores: Hetz, C., Lee, A. H., Gonzalez-Romero, D., Thielen, P., Castilla, J., Soto, C., Glimcher, L.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2008
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/241370
Acceso en línea:https://hdl.handle.net/10533/241370
Access Level:acceso abierto
Descripción
Sumario:The unfolded protein response (UPR) is a conserved adaptive reaction that increases cell survival under endoplasmic reticulum (ER) stress conditions. X-box-binding protein-1 (XBP-1) is a key transcriptional regulator of the UPR that activates genes involv