Molecular insights to a novel Caveolin-1-Rab5–Rac-1 signaling pathway important for metastatic cancer cell migration and invasion
Caveolin-1 (CAV1) is a membrane protein that promotes Rac1 activation, migration and invasion of melanoma and metastatic breast cancer cells by mechanisms that have remained elusive. Recent evidence has shown that CAV1 sequesters p85α, a GAP for the small
| Autores: | , , , , |
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| Formato: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2015 |
| País: | Chile |
| Idioma: | inglés |
| OAI Identifier: | oai:repositorio.anid.cl:10533/239851 |
| Acesso em linha: | https://hdl.handle.net/10533/239851 |
| Access Level: | acceso abierto |
| Resumo: | Caveolin-1 (CAV1) is a membrane protein that promotes Rac1 activation, migration and invasion of melanoma and metastatic breast cancer cells by mechanisms that have remained elusive. Recent evidence has shown that CAV1 sequesters p85α, a GAP for the small |
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