COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS

Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules...

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Autores: Cardenas, Juan Pablo, Covarrubias Pizarro, Paulo Cesar, Demergasso Semenzato, Cecilia Susana, Holmes, David Salway, Levican Jaque, Gloria Paz, Quatrini Nyqvist, Raquel Clara, Shmaryahu, Amir
Tipo de recurso: capítulo de libro
Estado:Versión publicada
Fecha de publicación:2011
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/165331
Acceso en línea:https://hdl.handle.net/10533/165331
Access Level:acceso abierto
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repository_id_str
dc.title.none.fl_str_mv COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
dc.title.libro.none.fl_str_mv BIOHYDROMETALLURGY: BIOTECH KEY TO UNLOCK MINERAL RESOURCES VALUE
title COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
spellingShingle COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
Cardenas, Juan Pablo
title_short COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
title_full COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
title_fullStr COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
title_full_unstemmed COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
title_sort COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS
dc.creator.none.fl_str_mv Cardenas, Juan Pablo
Covarrubias Pizarro, Paulo Cesar
Demergasso Semenzato, Cecilia Susana
Holmes, David Salway
Levican Jaque, Gloria Paz
Quatrini Nyqvist, Raquel Clara
Shmaryahu, Amir
dc.creator.libro.none.fl_str_mv Jiang, Tao
Liu, Xueduan
Qin, Wenqing
Qiu, Guanzhou
Wang, Haidong
Yang, Yu
author Cardenas, Juan Pablo
author_facet Cardenas, Juan Pablo
Covarrubias Pizarro, Paulo Cesar
Demergasso Semenzato, Cecilia Susana
Holmes, David Salway
Levican Jaque, Gloria Paz
Quatrini Nyqvist, Raquel Clara
Shmaryahu, Amir
author_role author
author2 Covarrubias Pizarro, Paulo Cesar
Demergasso Semenzato, Cecilia Susana
Holmes, David Salway
Levican Jaque, Gloria Paz
Quatrini Nyqvist, Raquel Clara
Shmaryahu, Amir
author2_role author
author
author
author
author
author
description Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.
publishDate 2011
dc.date.issued.none.fl_str_mv 2011
dc.date.accessioned.none.fl_str_mv 2016-12-27T21:49:45Z
2022-06-17T20:35:42Z
dc.date.available.none.fl_str_mv 2016-12-27T21:49:45Z
2022-06-17T20:35:42Z
dc.type.none.fl_str_mv Capitulo de libro
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dc.identifier.folio.none.fl_str_mv 11085045
dc.identifier.isbn.none.fl_str_mv 9787548703563 
dc.identifier.uri.none.fl_str_mv https://hdl.handle.net/10533/165331
identifier_str_mv 11085045
9787548703563 
url https://hdl.handle.net/10533/165331
dc.language.iso.none.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv instname: Conicyt
reponame: Repositorio Digital RI2.0
instname: Conicyt
reponame: Repositorio Digital RI 2.0
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dc.relation.set.none.fl_str_mv info:eu-repo/semantics/dataset/hdl.handle.net/10533/93479
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dc.publisher.editorial.none.fl_str_mv CENTRAL SOUTH UNIVERSITY PRESS
repository.name.fl_str_mv Repositorio ANID
repository.mail.fl_str_mv aletelier@anid.cl
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spelling Shmaryahu, AmirQuatrini Nyqvist, Raquel ClaraLevican Jaque, Gloria PazHolmes, David SalwayDemergasso Semenzato, Cecilia SusanaCovarrubias Pizarro, Paulo CesarCardenas, Juan Pablo2011https://hdl.handle.net/10533/165331http://purl.org/coar/access_right/c_abf2COMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMS167162CHINACardenas, Juan PabloCovarrubias Pizarro, Paulo CesarDemergasso Semenzato, Cecilia SusanaHolmes, David SalwayLevican Jaque, Gloria PazQuatrini Nyqvist, Raquel ClaraShmaryahu, AmirJiang, TaoLiu, XueduanQin, WenqingQiu, GuanzhouWang, HaidongYang, Yu2016-12-27T21:49:45Z2022-06-17T20:35:42Z2016-12-27T21:49:45Z2022-06-17T20:35:42Z2011Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.Bioleaching acidophiles inhabit environments with unusually high concentrations of iron that can potentially cause oxidative stress via the Fenton reaction in which dangerous reactive oxygen species (ROS) are generated. ROS can cause damage to proteins, nucleic acids, lipids and other macromolecules and thus have deleterious effects on cell growth and survival. Many of these microorganisms are chemolithotrophs with unusually high oxygen consumption rates that may exacerbate the problem of oxidative stress. Although some knowledge has been gained in recent years regarding the oxidative stress response in a few acidophiles, the general strategies used by them to face ROS challenges are still inadequately understood. Comparative genomics and multiple bioinformatic tools were used to explore 44 sequenced genomes of acidophilic bacteria and archaea in order to reconstruct their individual oxidative stress responses and to identify conserved strategies. The analyses revealed that acidophiles lack genes encoding typical oxidative stress response regulators and have an underrepresentation of classical ROS consumption enzymes (e.g. catalases) although they have a complete repertoire of repair systems for macromolecules (DNA, proteins and lipids). This suggests that stress mitigation is an active strategy in acidophiles confronting unavoidable ROS formation in their environment. Insights into the oxidative stress response in bioleaching acidophiles may contribute to a better understanding of the aspects that influence fitness of the microbial consortium driving bioleaching.FONDECYTFONDECYT110850459787548703563 https://hdl.handle.net/10533/165331engCENTRAL SOUTH UNIVERSITY PRESSinstname: Conicytreponame: Repositorio Digital RI2.0instname: Conicytreponame: Repositorio Digital RI 2.0info:eu-repo/grantAgreement/Fondecyt/11085045info:eu-repo/semantics/dataset/hdl.handle.net/10533/93479info:eu-repo/semantics/openAccessCOMPARATIVE GENOMICS OF THE OXIDATIVE STRESS RESPONSE IN BIOLEACHING MICROORGANISMSBIOHYDROMETALLURGY: BIOTECH KEY TO UNLOCK MINERAL RESOURCES VALUECapitulo de libroinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/bookPartCapituloLibrohttps://hdl.handle.net/10533/165331FONDECYThttp://purl.org/coar/resource_type/c_3248d3eb3ad7-d5a1-43fc-96c9-fa27118c3a90virtual::13286-1d3eb3ad7-d5a1-43fc-96c9-fa27118c3a90virtual::13286-110533/165331oai:repositorio.anid.cl:10533/1653312023-07-03 23:55:26.375https://repositorio.anid.clRepositorio ANIDaletelier@anid.cl
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