Copper-uptake is critical for the down regulation of synapsin and dynamin induced by neocuproine: modulation of synaptic activity in hippocampal neurons.

Extracellular and intracellular copper and zinc regulate synaptic activity and plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free intracellular cop

Detalles Bibliográficos
Autores: Castro, P. A., Ramirez, A., Sepúlveda, F. J., Peters, C., Fierro, H., Waldron, J., Luza, S., Fuentealba, J., Muñoz, F. J., De Ferrari, G. V., Bush, A. I., Aguayo, L. G., Opazo, C. M.
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:Chile
Idioma:inglés
OAI Identifier:oai:repositorio.anid.cl:10533/237876
Acceso en línea:https://hdl.handle.net/10533/237876
Access Level:acceso abierto
Descripción
Sumario:Extracellular and intracellular copper and zinc regulate synaptic activity and plasticity, which may impact brain functionality and human behavior. We have found that a metal coordinating molecule, Neocuproine, transiently increases free intracellular cop