Adaptor protein sorting nexin 17 regulates amyloid precursor protein trafficking and processing in the early endosomes
Accumulation of extracellular amyloid beta peptide (Abeta), generated from amyloid precursor protein (APP) processing by beta- and gamma-secretases, is toxic to neurons and is central to the pathogenesis of Alzheimer disease. Production of Abeta from APP
Bibliographic Details
| Authors: |
Lee, J.,
Retamal, C.,
Cuitiño, L.,
Caruano-Yzermans, A.,
Shin, J. E.,
van Kerkhof, P.,
Marzolo, M. P.,
Bu, G. |
| Format: | article
|
| Status: | Published version |
| Publication Date: | 2008 |
| Country: | Chile |
| Language: | English |
| OAI Identifier: | oai:repositorio.anid.cl:10533/240797 |
| Online Access: | https://hdl.handle.net/10533/240797
|
| Access Level: | Open access |