Characterization of eight new phlebotomus fever serogroup arboviruses (Bunyaviridae : Phlebovirus) from the Amazon region of Brazil

Eight new members of the phiebotomus fever arbovirus serogroup (family Bunyaviridae; genus Phlebovirus) from the Amazon region of Brazil are described. One serotype was recovered from a febrile patient, three from small wild animais and four from sand flies. A small serum survey carried out with the...

ver descrição completa

Detalhes bibliográficos
Autores: Rosa, Amélia Paes de Andrade Travassos da, Tesh, Robert B, Pinheiro, Francisco de Paula, Rosa, Jorge Fernando Soares Travassos da, Peterson, Norman E
Formato: artículo
Estado:Versión publicada
Fecha de publicación:1983
País:Brasil
Recursos:Instituto Evandro Chagas (IEC)
Repositorio:Repositório Digital do Instituto Evandro Chagas (Patuá)
Idioma:inglés
OAI Identifier:oai:patua.iec.gov.br:iec/2679
Acesso em linha:https://patua.iec.gov.br/handle/iec/2679
Access Level:acceso abierto
Palavra-chave:Antígenos Virais / imunologia
Bunyaviridae / classificação
Phlebotomus / microbiologia
Phlebotomus / imunologia
Testes de Fixação de Complemento
Ratos
Brasil (BR)
Descrição
Resumo:Eight new members of the phiebotomus fever arbovirus serogroup (family Bunyaviridae; genus Phlebovirus) from the Amazon region of Brazil are described. One serotype was recovered from a febrile patient, three from small wild animais and four from sand flies. A small serum survey carried out with the human isolate, Alenquer virus, suggests that it rarely infects man. Complement-fixation and plaque reduction neutralization tests were done, comparing the eight new viruses with other members of the phiebotomus fever serogroup. A close antigenic relationship was demonstrated between one of the new agents (Belterra) and Rift Valley fever virus. This finding is of considerable interest and deserves further investigation. Addition of these eight new viruses to the genus Phlebovirus brings to 14 the number of serotypes known to occur in the Amazon region and to 36 the total number reported worldwide. More detailed clinicai and epidemiological studies should be conducted in Amazónia in order to define the public health impact caused by phleboviruses.