A new flavonoid derivative from leaves of Oxandra Sessiliflora R. E. Fries

The ethyl acetate (EtOAc) phase obtained from the partition of the ethanol (EtOH) extract from leaves of O. sessiliflora R. E. Fries (Annonaceae) was subjected to several chromatographic steps, including high efficiency liquid chromatography (HPLC), to afford the flavonoids: quercetin-3-O-α-L-rhamno...

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Bibliographic Details
Authors: Sousa, Elcilene Alves de, Silva, Armenio Andre de Carvalho Almeida da, Cavalheiro, Alberto José, Lago, Joao Henrique Ghilardi [UNIFESP], Chaves, Mariana Helena
Format: article
Status:Published version
Publication Date:2014
Country:Brasil
Institution:Universidade Federal de São Paulo (UNIFESP)
Repository:Repositório Institucional da UNIFESP
Language:English
OAI Identifier:oai:repositorio.unifesp.br:11600/8355
Online Access:http://dx.doi.org/10.5935/0103-5053.20140023
http://repositorio.unifesp.br/handle/11600/8355
Access Level:Open access
Keyword:Oxandra sessiliflora
flavonoids
quercetin-3-O-α-L-rhamnopyranosyl-(14)-β-D-glucopyranoside
Description
Summary:The ethyl acetate (EtOAc) phase obtained from the partition of the ethanol (EtOH) extract from leaves of O. sessiliflora R. E. Fries (Annonaceae) was subjected to several chromatographic steps, including high efficiency liquid chromatography (HPLC), to afford the flavonoids: quercetin-3-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside (1), unprecedented in the literature, kaempferol-3-O-α-L-rhamnopyranosyl-(1→4)-β-D-glucopyranoside (2), rutin (3), and kaempferol-3-O-rutinoside (4). The structures were elucidated by analysis of their ¹H and 13C nuclear magnetic resonance (NMR) (1D and 2D) spectra and mass spectrometry.