Cardiorespiratory interactions in health and disease

Like dancers in perfect synchrony, the cardiovascular and respiratory systems perform their functions in a coordinated way. Rhythmical oscillations in arterial pressure and heart rate follow inspiration and expiration, contributing to optimizing tissue perfusion and gas exchange processes and suppor...

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Detalles Bibliográficos
Autores: Zoccal, Daniel B. [UNESP], Machado, Benedito H., Moraes, Davi J.A.
Tipo de recurso: capítulo de libro
Estado:Versión publicada
Fecha de publicación:2022
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/248518
Acceso en línea:http://dx.doi.org/10.1016/B978-0-323-85492-4.00043-0
http://hdl.handle.net/11449/248518
Access Level:acceso abierto
Palabra clave:Arterial pressure waves
Brainstem
Breathing
Cardiovascular diseases
Parasympathetic
Respiratory sinus arrhythmia
Sympathetic
Descripción
Sumario:Like dancers in perfect synchrony, the cardiovascular and respiratory systems perform their functions in a coordinated way. Rhythmical oscillations in arterial pressure and heart rate follow inspiration and expiration, contributing to optimizing tissue perfusion and gas exchange processes and supporting the emergence of appropriate cardiorespiratory responses in conditions of elevated metabolic demand. The cardiorespiratory interaction begins at the central nervous system level. The brainstem neurons responsible for breathing generation communicate with neurons that control sympathetic and parasympathetic activities, modulating their firing frequency. Changes in the strength and pattern of respiratory-autonomic interactions have been reported in experimental models of cardiovascular diseases, identifying the respiratory modulation of the cardiovascular function as a relevant therapeutical strategy to be considered in cardiovascular diseases.