Human cerebral organoids: Complex, versatile, and human-relevant models of neural development and brain diseases

This work was supported by the Grant PID2021-126715OB-I00 financed by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe”, by the Grant PI22CIII/00055 funded by Instituto de Salud Carlos III (ISCIII), and the UFIECPY 398/19 (PEJ2018-004965) grant to RGS funded by AEI (Spain), the UFIECP...

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Detalles Bibliográficos
Autores: Coronel, Raquel, González-Sastre, Rosa, Mateos-Martínez, Patricia, Maeso, Laura, Llorente-Beneyto, Elena, Martín-Benito, Sabela, Gagosian, Viviana S. Costa, Foti, Leonardo, González-Caballero, Ma Carmen, López-Alonso, Victoria, Liste, Isabel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2025
País:Brasil
Institución:Fundação Oswaldo Cruz (FIOCRUZ)
Repositorio:Repositório Institucional da FIOCRUZ (ARCA)
Idioma:inglés
OAI Identifier:oai:arca.fiocruz.br:icict/73510
Acceso en línea:https://arca.fiocruz.br/handle/icict/73510
Access Level:acceso abierto
Palabra clave:assembloides
bioengenharia
desafios
modelagem de doença
triagem de drogas e toxicologia
organoides cerebrais humanos
células-tronco pluripotentes humanas
doenças neurodegenerativas
neurodesenvolvimento
vascularização
assembloids
bioengineering
challenges
disease modeling
drug screening and toxicology
human brain organoids
human pluripotent stem cells
neurodegenerative diseases
neurodevelopment
vascularization
Descripción
Sumario:This work was supported by the Grant PID2021-126715OB-I00 financed by MCIN/AEI/10.13039/501100011033 and “ERDF A way of making Europe”, by the Grant PI22CIII/00055 funded by Instituto de Salud Carlos III (ISCIII), and the UFIECPY 398/19 (PEJ2018-004965) grant to RGS funded by AEI (Spain), the UFIECPY-396/19 (PEJ2018-004961) grant financed by MCIN (Spain) and FI23CIII/00003 grant funded by ISCIII-PFIS (Spain) to PMM, the UFIECPY 328/22 (PEJ-2021-TL/BMD-21001) grant to LM financed by CAM (Spain), and the grant by CAPES (Coordination for the Improvement of Higher Education Personnel), through the PDSE program (Programa de Doutorado Sanduíche no Exterior), to VSCG financed by MEC (Brazil).