Spot-test identification and rapid quantitative sequential analys is of dipyrone

A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results...

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Detalles Bibliográficos
Autores: Tubino, M., Biondo, A. C., Vila, M. M.D.C., Pezza, L. [UNESP], Pezza, H. R. [UNESP]
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2010
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/222640
Acceso en línea:http://dx.doi.org/10.26850/1678-4618EQJ.V35.1.2010.P41-46
http://hdl.handle.net/11449/222640
Access Level:acceso abierto
Palabra clave:Analysis
Dipyrone
Qualitative
Quantitative
Spot-test
Descripción
Sumario:A qualitative spot-test and tandem quantitative analysis of dipyrone in the bulk drug and in pharmaceutical preparations is proposed. The formation of a reddish-violet color indicates a positive result. In sequence a quantitative procedure can be performed in the same flask. The quantitative results obtained were statistically compared with those obtained with the method indicated by the Brazilian Pharmacopoeia, using the Student fst and the F tests. Considering the concentration in a 100 μL aliquot, the qualitative visual limit of detection is about (Formula Presented) instrumental (Formula Presented)