Seroepidemiological investigation on visceral larva migrans by Toxocara canis in health service users from Goiania, Brazil
A study on the frequency and risk factors related to visceral larva migrans (VLM)in 1,131 users of public and private laboratories in Goiania, Brazil, was performed. Antibodies anti-Toxocara canis were analyzed from sera by an immunoenzimaticassay (ELISA) employing as antigen, excretion and secretio...
| Autores: | , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión publicada |
| Fecha de publicación: | 2009 |
| País: | Brasil |
| Institución: | Universidade Federal de Goiás (UFG) |
| Repositorio: | Revista de patologia tropical (Online) |
| Idioma: | portugués |
| OAI Identifier: | oai:ojs.revistas.ufg.br:article/7838 |
| Acceso en línea: | https://revistas.ufg.br/iptsp/article/view/7838 |
| Access Level: | acceso abierto |
| Palabra clave: | Toxocara canis ELISA Visceral Larva Migrans Frequency. Larva migrans visceral Frequência. Parasitologia |
| Sumario: | A study on the frequency and risk factors related to visceral larva migrans (VLM)in 1,131 users of public and private laboratories in Goiania, Brazil, was performed. Antibodies anti-Toxocara canis were analyzed from sera by an immunoenzimaticassay (ELISA) employing as antigen, excretion and secretion products of thirdstage larvae of T. canis. In order to decrease the possibility of crossed reactionswith species of Ascaris genera, sera were treated previously with an extract ofAscaris suum. Samples were considered positive when optical density was above0.3. Qui-square tests were used for evaluation of differences of proportions.The frequency found was 18.9% (CI 95% 16.7-21.3). Besides serum collection,individuals that participated in the study, signed a consent form and were interviewedfor evaluation of the possible risk factors related with the transmission of viscerallarva migrans, such as: presence of dogs in the house and surroundings, historyof living in rural areas, drinking water resources, geophagia, use of river water,ingestion of vegetables without previous treatment, habit of washing hands beforemeals, manipulation of sand or earth. For evaluation of risk factors, odds ratio werecalculated, with the respective confidence intervals of 95%. The presence of dogsin houses and surroundings, history of geophagia and use of non filtered water wererisk factors statistically significant for transmission of VLM, after adjustment forpossible confounding variables. Even if the percentage of 18.9% of serum positivitycannot be extrapolated for the urban population of Goiania, results obtained suggestan elevated frequency of the infection by T. canis in this region. |
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