Demyelinating disease in patients with myasthenia gravis

Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare...

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Detalhes bibliográficos
Autores: Bichuetti, Denis Bernardi [UNIFESP], Barros, Tatiane Martins de [UNIFESP], Oliveira, Enedina Maria Lobato de [UNIFESP], Annes, Marcelo [UNIFESP], Gabbai, Alberto Alain [UNIFESP]
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2008
País:Brasil
Recursos:Universidade Federal de São Paulo (UNIFESP)
Repositório:Repositório Institucional da UNIFESP
Idioma:inglês
OAI Identifier:oai:repositorio.unifesp.br:11600/4259
Acesso em linha:http://dx.doi.org/10.1590/S0004-282X2008000100002
http://repositorio.unifesp.br/handle/11600/4259
Access Level:Acceso aberto
Palavra-chave:myasthenia gravis
myelinating disease
association
miastenia gravis
doenças desmielinizante
associação
Descrição
Resumo:Myasthenia gravis (MG) is an autoimmune disease characterized by fluctuating muscle weakness, caused by impaired neuromuscular transmission. Patients with MG can present other autoimmune diseases in association, commonly hypo or hyperthyroidism. The association of MG to demyelinating disease is rare and has been described before. We report on three Brazilian patients with MG that presented distinct demyelinating diseases, two monophasic and one recurrent neuromyelitis optica, several years after the diagnosis of MG, and discuss their clinical courses.