Antipsicóticos de ação prolongada no tratamento de manutenção da esquizofrenia. Parte II. O manejo do medicamento, integração da equipe multidisciplinar e perspectivas com a formulação de antipsicóticos de nova geração de ação prolongada

Among various topics, this second part addresses indication and beginning of treatment, dose inter-individual variability and interval between injections, appointment frequency and special strategies during treatment relapse. Considering that poor adherence to antipsychotic treatment is a major fact...

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Bibliographic Details
Author: Bechelli, Luiz Paulo de C.
Format: article
Status:Published version
Publication Date:2003
Country:Brasil
Institution:Universidade de São Paulo (USP)
Repository:Revista Latino-Americana de Enfermagem (Online)
Language:Portuguese
OAI Identifier:oai:revistas.usp.br:article/1795
Online Access:https://www.revistas.usp.br/rlae/article/view/1795
Access Level:Open access
Keyword:antipsychotic
long-acting antipsychotic
depot antipsychotic
schizophrenia
antipsicótico
antipsicótico de acción prolongada
antipsicótico depot
esquizofrenia
antipsicótico de ação prolongada
Description
Summary:Among various topics, this second part addresses indication and beginning of treatment, dose inter-individual variability and interval between injections, appointment frequency and special strategies during treatment relapse. Considering that poor adherence to antipsychotic treatment is a major factor in schizophrenic relapse, that the new generation of antipsychotic drugs, despite lower incidence of extrapyramidal side effects and better overall tolerability, did not change this condition in relation to conventional drugs and in view of the superiority of depot antipsychotics in comparison with conventional ones administered orally, the long-acting formulation of new generation antipsychotics can certainly improve the adherence and regularity of the medication regimen and decrease relapse rates in patients with schizophrenia. Furthermore, family participation in treatment is of great importance, as well as the attitude and integration of the medical team in realizing different tasks.