Electrochemical Determination of Norepinephrine by Means of Modified Glassy Carbon Electrodes with Carbon Nanotubes and Magnetic Nanoparticles of Cobalt Ferrite

This study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo98). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission e...

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Detalles Bibliográficos
Autores: Queiroz, Daniely Ferreira de, Lima Dadamos, Tony Rogerio de [UNESP], Spinola Machado, Sergio Antonio, Utrera Martines, Marco Antonio
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2018
País:Brasil
Institución:Universidade Estadual Paulista (UNESP)
Repositorio:Repositório Institucional da UNESP
Idioma:inglés
OAI Identifier:oai:repositorio.unesp.br:11449/164816
Acceso en línea:http://dx.doi.org/10.3390/s18041223
http://hdl.handle.net/11449/164816
Access Level:acceso abierto
Palabra clave:electrode modified
cobalt ferrite
noradrenaline
Descripción
Sumario:This study describes the electrochemical preparation of the electrocatalytic oxidation/reduction of noradrenaline in modified glassy carbon of cobalt ferrite nanoparticles and carbon nanotubes (GC/MWCNT/FCo98). The cobalt ferrite powder was characterized by X-ray diffraction (XRD) and transmission electron microscopy (TEM). The optimum conditions found in an electrode composition were 4 mu L of cobalt ferrite and 10 mu L of carbon nanotubes in 0.1 mol L-1 PBS at pH 7.0. The electrode displays electrochemical behavior in a wide potential range (-0.4 to 1.0 V vs. Ag/AgCl), high conductivity, and electrode stability/durability in 0.1 mol L-1 PBS. Catalytic oxidation of noradrenaline was performed at the unmodified GC electrode at +0.60 V vs. Ag/AgCl and current of 0.17 mu A and modified GC with cobalt ferrite nanoparticles and carbon nanotubes at +0.54 V vs. Ag/AgCl and current of 0.23 mA. With regard to the anodic peak current (I-pa) versus noradrenaline concentration by means of the amperometric method at the modified electrode, (which is linear in the 0.16 and 1.91 mmol L-1 concentration range), the concentration limit was 0.76 mu mol L-1. In this way, the modified electrode GC/MWCNT/FCo98 was found to be a promising application for the determination of this neurotransmitter in the area of neuroscience.