Evaluation of insulin resistance in individuals with severe obesity candidates for bariatric surgery

Severe obesity is a disease that has reached worldwide proportions, and consequent increase in surgical treatment. This, besides reducing body fat, also helps to reduce associated comorbidities, such as insulin resistance (IR) and diabetes. The aim of this study was to evaluate IR in obese individua...

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Detalhes bibliográficos
Autores: Almeida, Vivian Cristhyna Alves, Guimarães, Nathália Sernizon, Sá, Cristiane Maria Araújo Tavares de, Costa, Manoel da Cunha, Burgos, Maria Goretti Pessoa de Araújo, Vilar, Lucio, Vieira, Renata Adrielle Lima
Formato: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:Brasil
Recursos:Instituto Brasileiro de Ensino e Pesquisa em Fisiologia do Exercício (IBPEFEX)
Repositorio:Revista brasileira de obesidade, nutrição e emagrecimento
Idioma:portugués
OAI Identifier:oai:ojs.www.rbone.com.br:article/2305
Acesso em linha:https://www.rbone.com.br/index.php/rbone/article/view/2305
Access Level:acceso abierto
Palavra-chave:Morbid obesity
Bariatric surgery
Insulin resistance
Obesidad morbida
Cirugia bariátrica
Resistencia a la insulina
Obesità patologica
Chirurgia bariatrica
Resistenza all'insulina
Obesidade mórbida
Cirurgia bariátrica
Resistência à insulina
Descrição
Resumo:Severe obesity is a disease that has reached worldwide proportions, and consequent increase in surgical treatment. This, besides reducing body fat, also helps to reduce associated comorbidities, such as insulin resistance (IR) and diabetes. The aim of this study was to evaluate IR in obese individuals in the preoperative period of bariatric surgery. A cross-sectional study was carried out with patients admitted for bariatric surgery at Hospital Universitário Oswaldo Cruz (HUOC-UPE) in Recife-PE. Insulin resistance was assessed by triglyceride-glucose index (TyG index) and Triglyceride/HDL-c ratio (TG/HDL). Body composition was obtained by dual X-ray emission densitometry (DEXA). Sociodemographic data, anthropometric and biochemical variables, physical activity level, and alcohol intake were also collected. Sixty patients participated, with a mean age of 38.88 ±9.67 years, the majority being female, with an education level of more than 10 years, classified as active and at low risk for alcohol dependence. Men presented significantly higher values for weight, neck circumference, waist circumference and lean body mass (Kg). The candidates had IR, by TyG index and TG/HDL ratio, with females showing higher TyG index (p=0.037). Therefore, evaluating insulin resistance by easily accessible parameters in the preoperative period allows the adoption of early intervention strategies and thus reduce the consequences from its non-treatment.